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妇炎康联合阿奇霉素治疗盆腔炎性疾病的临床观察
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| 篇名： | 妇炎康联合阿奇霉素治疗盆腔炎性疾病的临床观察 |
| TITLE： | |
| 摘要： | 目的：观察妇炎康联合阿奇霉素治疗妇科盆腔炎性疾病的临床疗效及安全性。方法：选择盆腔炎性疾病患者90例，按随机数字表法分为观察组和对照组，各45例。对照组患者给予乳糖酸阿奇霉素注射液首次剂量500 mg，ivgtt，qd，随后改为阿奇霉素胶囊250 mg，po，qd；观察组患者在对照组基础上加服妇炎康片1.56 g，tid。两组患者均7 d为1个疗程，连续治疗3个疗程。观察两组患者临床疗效及治疗前后C反应蛋白（CRP）、白细胞介素（IL）2水平及生活质量评分，并比较不良反应发生情况。结果：观察组患者临床总有效率为97.78％，显著高于对照组的86.67％，差异有统计学意义（P＜0.05）。治疗后，两组患者CRP、IL-2水平及生活质量评分均显著改善，且观察组明显优于对照组，差异均有统计学意义（P＜0.05）。两组患者治疗期间均未见明显不良反应发生。结论：妇炎康联合阿奇霉治疗妇科盆腔炎性疾病疗效显著，能有效提高患者的生活质量，减少炎性因子浸润及炎性介质的生成，且安全性较好。 |
| ABSTRACT： | OBJECTIVE： To observe the clinical efficacy and safety of Fuyankang combined with azithromycin in the treatment of pelvic inflammatory disease. METHODS： 90 patients with pelvic inflammatory disease were selected and randomly divided into observation group and control group， with 45 cases in each group. Control group was given Lactose acid azithromycin for injection 500 mg， ivgtt， qd， and then Azithromycin capsule 250 mg， po， qd； observation group was additionally given Fuyankang Tablet 1.56 g， tid， on the basis of control group. A treatment course of 2 groups lasted for 7 d， and both received 3 courses of treatment. Clinical efficacies of 2 groups were observed as well as the level of CRP， IL-2 and life quality score before and after treatment， and the occurrence of ADR was compared between 2 groups. RESULTS： Total effective rate of observation group was 97.78％， which was significantly higher than that of control group （86.67％）， with statistical significance （P＜0.05）. The level of CRP， IL-2 and life quality score of 2 groups were improved significantly after treatment， and the observation group was more better than the control group， with statistical significance （P＜0.05）. No obvious ADR was found in 2 groups during treatment. CONCLUSIONS： Fuyankang combined with Azithromycin is effective for pelvic inflammatory disease， and can improve the quality of life， reduce inflammation cytokines infiltration and the generation of inflammatory medium with good safety. |
| 期刊： | 2016年第27卷第29期 |
| 作者： | 任秀如，朱慧芳，沈宏杰，王进 |
| AUTHORS： | REN Xiuru，ZHU Huifang，SHEN Hongjie，WANG Jin |
| 关键字： | 妇炎康；阿奇霉素；中西医结合；盆腔炎性疾病；C反应蛋白；白细胞介素2 |
| KEYWORDS： | Fuyankang； Azithromycin； Integrated traditional and western medicine； Pelvic inflammatory disease； CRP； IL-2 |
| 阅读数： | 309 次 |
| 本月下载数： | 1 次 |
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