中老年膝关节慢性滑膜炎患者关节镜下清理术后应用芪志祛湿健脾方的临床观察
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篇名: 中老年膝关节慢性滑膜炎患者关节镜下清理术后应用芪志祛湿健脾方的临床观察
TITLE:
摘要: 目的:观察中老年慢性膝关节滑膜炎患者关节镜下清理术后应用芪志祛湿健脾方的临床疗效和安全性。方法:选取中老年膝关节慢性滑膜炎住院患者80例,按照随机数字表法分为治疗组和对照组,各40例。观察两组患者的临床疗效,采用视觉模拟评分(VAS)法评价患者疼痛程度,采用改良Cincinnati膝关节评分系统评价患者关节肿胀程度,采用Lysholm评分评价膝关节功能,观察治疗组患者的不良反应发生情况。结果:治疗组患者的总有效率(92.5%)明显高于对照组(77.5%),差异有统计学意义(P<0.05)。关节镜下清理术术前,两组患者膝关节VAS评分、肿胀评分和Lysholm评分比较,差异均无统计学意义(P>0.05)。术后第1天,两组患者VAS评分均明显下降,与术前比较差异有统计学意义(P<0.05);术后1个月,两组患者VAS评分明显下降,且治疗组患者明显低于对照组,差异有统计学意义(P<0.05)。两组患者术后1个月时的膝关节肿胀评分及术后3个月时的Lysholm评分均明显上升,且治疗组患者明显高于对照组,差异有统计学意义(P<0.05)。治疗组患者有5例出现胃部不适,加味合胃利湿中药后症状减轻。结论:中老年慢性膝关节滑膜炎患者关节镜下清理术后应用芪志祛湿健脾方的临床疗效较好,可缓解疼痛,消除肿胀和恢复膝关节功能,且安全性较好。
ABSTRACT: OBJECTIVE: To observe clinical efficacy and safety of Qizhi qushi jianpi prescription in the treatment of chronic synovitis of knee joint in middleaged and elderly patients after debridement under arthroscope. METHODS: A total of 80 middleaged and elderly inpatients with chronic synovitis of knee joint were selected and randomly divided into treatment group and control group, with 40 cases in each group. Clinical efficacy, VAS, swelling score of modified Cincinnati knee joint score system, Lysholm score of knee joint function, the occurrence of ADR were observed in 2 groups. RESULTS: Total effective rate of treatment group (92.5%) was significantly than that of control group (77.5%), with statistical significance (P<0.05). Before debridement under arthroscope, there was no statistical significance in VAS score of knee joint, swelling score and Lysholm score between 2 groups (P>0.05). On the first day after surgery, VAS score of 2 groups decreased significantly, and there was statistical significance compared to before surgery (P<0.05). One month after surgery, VAS score of 2 groups decreased significantly, and the treatment group was significantly lower than the control group, with statistical significance (P<0.05). Swelling score of knee joint 1 month after surgery and Lysholm score 3 months after surgery increased significantly in 2 groups, and the treatment group was significantly higher than the control group, with statistical significance (P<0.05). 5 patients of treatment group suffered from stomach discomfort, and the symptom was relieved after adding the ingredient of comforting stomach and removing dampness through diuresis. CONCLUSIONS: Qizhi qushi jianpi prescription is effective for chronic synovitis of knee joint in middleaged and elderly patients after debridement under arthroscope, and can relieve pain, remove swelling and recover knee joint function with good safety.
期刊: 2016年第27卷第29期
作者: 李立强,于健,杨家祥,田巍,张欲翔,田伟明
AUTHORS: LI Liqiang,YU Jian,YANG Jiaxiang,TIAN Wei,ZHANG Yuxiang,TIAN Weiming
关键字: 芪志祛湿健脾方;关节镜下清理术;膝关节慢性滑膜炎;疗效观察
KEYWORDS: Qizhi qushi jianpi prescription; Debridement urder arthroscope; Chronic synovitis of knee joint; Efficacy observation
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