应用国际指南评价某院外科住院患者人血白蛋白临床使用情况
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篇名: 应用国际指南评价某院外科住院患者人血白蛋白临床使用情况
TITLE:
摘要: 目的:为外科住院患者人血白蛋白临床合理使用提供参考。方法:分析某院外科2014年1-3月住院患者人血白蛋白的使用情况,并以美国大学医院联合会(UHC)制订的《人血白蛋白、非蛋白胶体及晶体溶液使用指南》(2010版)和欧洲《免疫球蛋白及白蛋白使用推荐》为标准进行评价。结果:556例患者共提交了895份人血白蛋白使用申请,主要集中在胃肠外科(29.7%)、肝胆外科(25.9%)和胸心外科(13.1%)。主要的用药理由为纠正低白蛋白血症(62.9%),其次是大手术期间的白蛋白补充(7.9%)和减轻肝硬化患者的腹水(4.4%);仅95份(10.6%)人血白蛋白申请理由符合指南适应证。最主要的不适宜用药理由为纠正低白蛋白血症。结论:该院外科住院患者人血白蛋白用量大,且其适应证与指南相符率低,需加强人血白蛋白的合理、规范使用。
ABSTRACT: OBJECTIVE: To provide reference for rational use of human serum albumin for surgical inpatients. METHODS: The utilization of human serum albumin for surgical inpatients in a hospital during Jan.-Mar. 2014 was analyzed and evaluated by UHC Guidelines for the Use of Album, Nonprotein Colloid, and Crystalloid Solutions (2010 edition) and European Immune Globulin and Albumin Use Recommendation. RESULTS: Among the 556 patients, totally 895 human serum albumin application were conducted, mainly involving development of gastrointestinal surgery (29.7%), hepatobiliary surgery (25.9%) and cardiothoracic surgery (13.1%). The main reasons were correcting hypoalbuminemia (62.9%), followed by albumin supplemented during major surgery (7.9%) and alleviating ascites in patients with cirrhosis (4.4%); only 95 applications (10.6%) were considered appropriate. The most prevalent inappropriate reason was for correcting hypoalbuminemia. CONCLUSIONS: Human serum albumin in the surgical inpatients in the hospital shows a large amount, and low consistent rate between indications and guidelines. The rational standardized utilization of human serum albumin should be strengthened.
期刊: 2016年第27卷第29期
作者: 蒙龙,王宁,冯然,汪盼,陈邕
AUTHORS: MENG Long,WANG Ning,FENG Ran,WANG Pan,CHEN Yong
关键字: 人血白蛋白;回顾性调查;临床应用;国际指南
KEYWORDS: Human serum albumin; Retrospective study; Clinical application; International guidance
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