我国七地区78家样本医院2013-2014年儿童患者用药分析
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篇名: 我国七地区78家样本医院2013-2014年儿童患者用药分析
TITLE:
摘要: 目的:分析我国儿童用药现状,为促进我国儿童药品的研发和供给提供参考。方法:分析中国药学会医院药学专业委员会“医院处方分析合作项目”抽样的北京、上海、天津、杭州、郑州、广州、成都七地区78家医院2013-2014年2 632 514人次0~14岁儿童患者的处方用药数据,运用Access和Excel软件进行统计分析。结果:七地区78家样本医院2013-2014年儿童患者共使用1 572种药品,但仅有31.04%的品种为儿童药品,且各类药品中儿童药品品种数占比和儿童药品使用频次占比差别较大。注射给药途径药品的使用频次占比为57.97%,远高于口服给药途径(31.04%)。儿童患者使用的口服固体制剂药品中规格不合理药品的使用频次占比为29.57%,品种数占比为40.99%。结论:七地区78家样本医院2013-2014年儿童患者存在用药品种、用药剂型和用药规格等多方面短缺,造成临床药物治疗中儿童患者出现超说明书用药、注射剂使用率高、掰片用药等不合理现象,存在较大的用药风险。建议国家强化和完善儿童药品研发和供给激励机制,以解决我国儿童药品短缺问题,促进儿童临床药物治疗的合理化,保障儿童用药安全。
ABSTRACT: OBJECTIVE: Analyze drug use of pediatrics in China, and to provide reference for promoting  research, development and supply of pediatric drugs. METHODS: Analyze the data of drug use in 2 632 514 pediatric patients aged from 0 to 14 of 78 sample hospitals from Beijing, Shanghai, Tianjin, Hangzhou, Zhengzhou, Guangzhou and Chengdu in “The Hospital Prescriptions Cooperation Project” of Hospital Pharmacy Professional Committee of Chinese Pharmaceutical Association, statistical analysis was performed by using Excel and Access software. RESULTS: Pediatric patients in 78 sample hospitals of 7 regions had used 1 572 kinds of drugs from 2013 to 2014, but only 31.04% of drugs were pediatric drugs; both the ratio of pediatric drug types and the ratio of pediatric drugs use frequency had a great gap in different drug classifications. The ratio of drug use frequency in injection administration was 57.97%, and it was greatly higher than that of oral administration (31.04%). Among oral solid preparations, the ratio of drug use frequency for drugs with unreasonable specification was 29.57%, and ratio of drug types was 40.99%. CONCLUSIONS: The pediatric patients had a great drug shortage in kinds, dosage forms and specifications in 78 sample hospitals of 7 regions during 2013-2014. Off-label drug use, high frequence of injection use, tablets used after breaking and other irrational phenomena were found in pediatric patients during clinical drug therapy, which reduced high risk of drug use. It is recommended that government should strengthen and improve incentives mechanism of research, development and supply of pediatric drugs, so as to solve pediatric drug shortage in China, promote rational clinical drug therapy for children and guarantee the safety of drug use in pediatrics.
期刊: 2016年第27卷第29期
作者: 李逸云,武志昂,胡欣
AUTHORS: LI Yiyun,WU Zhi’ang,HU Xin
关键字: 儿童患者;儿童药品;药品短缺;用药分析
KEYWORDS: Pediatric patients; Pediatric drugs; Drug shortage; Analysis of drug use
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