南京地区34家医院2012-2014年平喘药使用分析
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篇名: 南京地区34家医院2012-2014年平喘药使用分析
TITLE:
摘要: 目的:为平喘药的临床合理使用提供参考。方法:采用回顾性分析方法,对南京地区34家医院2012-2014年平喘药的应用品种、销售金额及用药频度(DDDs)等进行统计分析。结果:2012-2014年,南京地区34家医院平喘药销售金额及DDDs均逐年增加,年均增长率分别为29.54%、22.11%;抗胆碱药、β2受体激动药和抗过敏药始终占据平喘药市场的主导地位,三者的DDDs之和占总DDDs的比例均>80%,且呈逐年上升趋势。抗过敏药的DDDs构成比上升明显,中成药类的DDDs构成比下降明显。给药途径为吸入的平喘药DDDs最大,构成比均>65%;给药途径为口服的平喘药销售金额最高,构成比均>40%。销售金额排名前2位的药品为孟鲁司特钠和噻托溴铵;DDDs排名前3位的药品为溴化异丙基阿托品、沙丁胺醇和孟鲁司特钠。结论:南京地区34家医院2012-2014年各亚类平喘药的销售金额和DDDs构成比相对稳定,抗胆碱药为平喘治疗的首选用药,短效缓解性药物是销售金额和用量增长的主要贡献者。反映出患者对疾病的认识不够充分,临床用药不合理现象较多,应加强对医护人员的监督,规范患者遵医行为,以达到更好的预防监测病情、合理用药、最终控制病情的目的。
ABSTRACT: OBJECTIVE: To provide reference for rational use of antiasthmatic drugs in the clinic. METHODS: In retrospective study, the utilization of antiasthmatic drugs in 34 hospitals from Nanjing area during 2012-2014 was analyzed statistically in respects of varieties, consumption sum, DDDs, etc. RESULTS: During 2012-2014, the consumption sum and DDDs of antiasthmatic drugs in 34 hospitals from Nanjing area increased year by year, and the annual growth rates were 29.54% and 22.11%, respectively; anticholinergic drugs, β2 agonists and anti-allergic agents dominated the antiasthmatic market all the time; the sum of the DDDs of them accounted for more than 80% of the total DDDs, and it’s rising year by year; DDDs ratio of antiallergic increased obviously, while that of Chinese patent medicine decreased significantly. DDDs of antiasthmatic drugs for inhalation use was the highest, and their ratio were all >65%; consumption sum of antiasthmatic drugs for oral use was the highest, and their ratio were all >40%. Top 2 drugs in the list of consumption sum were montelukast sodium and tiotropium bromide; top 3 drugs in the list of DDDs were ipratropium bromide, salbutamol and montelukast sodium. CONCLUSIONS: The consumption sum and DDDs ratio of subtypes of antiasthmatic drugs keep stable relatively in 34 hospitals from Nanjing area during 2012-2014, anticholinergic drugs is the first choice for antiasthmatic therapy, short-acting remission drug is main contributor for the increase of consumption sum and amount. The understanding of patients to disease is not enough, and irrational drug use is common in the clinic. It is suggested to strengthen physicians and nurses supervision and standardize compliance behavior so as to obtain good effect of disease prevention and monitoring, rational drug use, disease control.
期刊: 2016年第27卷第14期
作者: 朱文婷,王羽,罗雪梅,刘慧
AUTHORS: ZHU Wenting,WANG Yu,LUO Xuemei,LIU Hui
关键字: 平喘药;销售金额;用药频度;用药分析
KEYWORDS: Antiasthmatic drugs; Consumption sum; DDDs; Analysis of drug use
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