EQ-5D健康量表效用积分体系的构建研究——基于我国西南地区的实证分析
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篇名: EQ-5D健康量表效用积分体系的构建研究——基于我国西南地区的实证分析
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摘要: 目的:构建一套基于我国西南地区全人群、城市及农村人群偏好的欧洲五维健康量表(EQ-5D)效用积分体系,旨在为该地区采用此量表进行成本-效用分析提供有效的健康效用值计算方法。方法:以贵州省为例,选取该省内年满16周岁的城市及农村人群各240例作为受访者,对其采用时间权衡法直接测量EQ-5D中97个健康状态的效用值,在个人及均值水平数据上分别构建计量经济学模型,最后根据模型预测能力、系数显著性、拟合优度等选择最优的预测模型。结果:共发放481份问卷,回收有效问卷467份,有效率为97.09%。贵州省全人群、城市及农村人群EQ-5D效用积分体系可分别通过基于均值水平数据的N3模型及主效应模型获取。该地区城市人群对中度、重度健康状态的评价值普遍低于农村人群。农村人群更看重行动、日常活动及自我照顾3个健康维度,而城市人群更在乎反映精神健康的焦虑或抑郁维度。结论:本研究结果可为我国西南地区医疗卫生资源配置及相关决策分析提供依据。
ABSTRACT: OBJECTIVE: To establish EQ-5D value sets for the whole southwest population, local urban and country people of southwest area of China, in order to provide an effective method to calculate utility values when conducting cost-utility analysis using EQ-5D. METHODS: Taking Guizhou province as example, 240 urban and country population aged over 16 years were selected as respondents. Utility values for a subset of 97 health states defined by the EQ-5D descriptive system were directly elicited by applying TTO technique. Econometric model was establish on the basis of individual and mean value. The predictive ability, adjusted R2, mean absolute error, etc. were used to choose the best model. RESULUTS: A total of 481 questionnaires were sent out and 467 valid questionnaires were collected with the effective rate of 97.09%. EQ-5D value sets for the whole population, local urban and country people of Guizhou province could be obtained by N3 model and the main effects at the average level. The southwest population from urban tended to give lower values to the moderate and severe heath states compared them from country. The country people gave greater weight to mobility, usual activities and self-care, while the urban people gave greater weight to anxiety/depression. CONCLUSIONS: The study can provide reference for medical resource allocation and decision-making in southwest of China.
期刊: 2016年第27卷第14期
作者: 伍红艳,刘国恩,官海静
AUTHORS: WU Hongyan,LIU Guo’en,GUAN Haijing
关键字: 欧洲五维健康量表;效用积分体系;时间权衡法;成本-效用分析;西南地区;贵州省
KEYWORDS: EQ-5D; Value set; TTO technique; Cost-utility analysis; Southwest area; Guizhou province
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