在美国申请的艾滋病疫苗专利分析
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篇名: 在美国申请的艾滋病疫苗专利分析
TITLE:
摘要: 目的:了解在美国申请的艾滋病(即获得性免疫缺陷综合征,AIDS)疫苗专利情况,为我国艾滋病疫苗的研发提供参考。方法:采用HIV vaccine(s)、AIDS vaccine(s)、Vaccine of HIV(AIDS)等关键词和A61K、A61P、C12P等分类号相结合的方法,在Thomson Innovation平台检索1981年1月-2015年3月的相关专利,对检索到的专利数据及其专利申请发展趋势、机构研发能力概况、专利技术领域分布等进行分析。结果:共检索到1 272项专利,其中有效专利405项。AIDS疫苗专利申请量从1985-2014年经历了缓慢上升期、快速上升期和缓慢下降期,总体呈上升趋势;研发实力较强的机构有杜克大学、美国卫生及公共服务部、巴斯德研究所、康诺特公司以及默克公司;AIDS疫苗的研发重点集中在医药配制品、药物治疗活性、微生物、酶等方面,其中美国科研机构在医药配制品和多肽的研究上关注较多。结论:艾滋病疫苗领域虽整体发展缓慢,但还有很大的上升空间。美国的科研机构在该领域具备较强的专利优势和科研实力。艾滋病疫苗的研发以医药配制品、药物治疗活性及组合物为主。
ABSTRACT: OBJECTIVE: To provide reference for AIDS vaccine R&D in China through investigating AIDS vaccine patent approval in America. METHODS: By combining keywords as HIV vaccine(s), AIDS vaccine(s) and Vaccine of HIV(AIDS) and classification number as A61K, A61P and C12P, related patents were retrieved from Thomson Innovation platform during Jan. 1981-Mar. 2015, and then analyzed in respects of patent data, patent approval trend, R&D ability, patent technology field distribution, etc. RESULTS: A total of 1 272 patents were retrieved, including 405 valid patents. From 1985 to 2014, there were three stages for the change of AIDS vaccine application quantity, which were slow rise, fast rise and slow decline period; on the whole, the trend was on the rise. The main players were Duke University, United States Department of Health and Human Services, Pasteur Institute, Connaught Laboratories Limited and Merck Group. AIDS vaccine R&D focused on pharmaceutical preparation, therapeutic activity of medicinal preparations, microorganism, enzyme, etc. American scientific research institutions focused more on pharmaceutical preparation and peptide study. CONCLUSIONS: Though the AIDS vaccine field develops slowly, the future is still promising. In this field, America has stronger patent advantage and scientific research strength. AIDS vaccine R&D concentrates on pharmaceutical preparation, therapeutic activity of medicinal preparations and composition.
期刊: 2016年第27卷第7期
作者: 秦雪梅,张冬梅
AUTHORS: QIN Xuemei,ZHANG Dongmei
关键字: 艾滋病;疫苗;专利;美国
KEYWORDS: AIDS; Vaccines; Patent; America
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