我院2010-2014年头孢菌素类药物使用分析
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篇名: 我院2010-2014年头孢菌素类药物使用分析
TITLE:
摘要: 目的:为头孢菌素类药物临床合理使用提供参考。方法:根据销售金额、限定日剂量(DDD)、日均费用(DDC)、用药频度(DDDs)等客观指标,对我院2010-2014年头孢菌素类抗菌药物使用情况进行动态分析。结果:我院2010-2014年,抗菌药物销售总金额占药品总金额的比例均保持在30%以下,且呈逐渐降低的趋势,由2010年的27.35%下降至2014年的14.70%。在各类抗菌药物中,头孢菌素类的销售金额占比及DDDs均最高,但销售金额占比呈逐年下降的趋势,由2010年的44.05%下降至2014年的30.49%,DDDs呈逐年上升趋势,由2010年的11.00×104上升至2014年的14.22×104;其中,第二代头孢菌素销售金额及DDDs连续5年均最高。各年度头孢替安销售金额均排名第1;2010-2011年头孢丙烯DDDs排名第1,2012-2014年则为头孢替安。2010-2011年头孢匹罗DDC最高,2012-2014年则为头孢孟多,说明该药价格高。各年度头孢丙烯、头孢呋辛的序号比均>1,说明该药价格较便宜,使用率较高;大多数药物的序号比接近1。结论:我院头孢菌素类药物应用日益趋于合理,但仍需进一步加强抗菌药物合理使用的宣传和监管。
ABSTRACT: OBJECTIVE: To provide reference for rational application of cephalosporins in the clinic. METHODS: The application of cephalosporins antibiotics in our hospital during 2010-2014 was analyzed dynamically in respects of consumption sum, DDD, DDC, DDDs, etc. RESULTS: During 2010-2014, the proportion of total consumption sum of antibiotics in total consumption sum kept below 30%, and decreased year by year, decreasing from 27.35% in 2010 to 14.70% in 2014. Among antibiotics, the consumption sum and DDDs of cephalosporins were the highest; consumption sum decreased year by year, decreasing from 44.50% in 2010 to 30.49% in 2014; DDDs increased year by year, increasing from 11.00×104 in 2012 to 14.22×104 in 2014. The consumption sum and DDDs of second generation cephalosporins were the highest. The consumption sum of cefotiam ranked the first place; DDDs of cefprozi ranked the first place during 2010-2011, while cefotiam ranked the first place during 2012-2014. DDC of cefpirome was the highest during 2010-2011, and that of cefamandole was the highest during 2012-2014, indicating it was expensive. The serial number ratio of cefprozi and cefuroxim was always >1 during those years, which indicated it was cheap and used frequently; that of most drugs were close to 1. CONCLUSIONS: The application of cephalosporins in our hospital tend to be rational, but  the propaganda and supervision of rational use of antibiotics should be further strengthened.
期刊: 2016年第27卷第5期
作者: 王建青,刘丽萍,杨琍琦
AUTHORS: WANG Jianqing,LIU Liping,YANG Liqi
关键字: 抗菌药物;头孢菌素;用药频度;用药分析
KEYWORDS: Antibiotics; Cephalosporin; DDDs; Analysis
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