常用老年人潜在不适当用药判断标准比较
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篇名: 常用老年人潜在不适当用药判断标准比较
TITLE: Comparison of commonly used judgment criteria for potentially inappropriate medication in the elderly
摘要: 目的 比较5种常用老年人潜在不适当用药(PIM)判断标准,为临床选择适宜的老年人PIM评价工具提供参考。方法从适用年龄及内容、量表特征方面分析和比较国内外常用的5种老年人PIM判断标准,即Beer’s标准、STOPP/STARTv2标准、ACOVE3标准、PIM-Check标准以及“中国老年人潜在不适当用药判断标准”(中国标准)。结果5种标准在量表特征方面既有重叠又有所侧重。在各研究中,依据的标准不同,PIM的发生率不同;质子泵抑制剂、利尿剂、非甾体抗炎药以及抗凝药是各标准出现最高频的老年人PIM涉及药物。结论结合患者的具体情况并充分考量治疗效益与风险,合理选择和联用5种PIM判断标准、对我国的PIM判断标准进行必要的补充,有助于提高临床医师和药师对老年患者治疗用药的有效性和安全性。
ABSTRACT: OBJECTIVE To compare five com monly used judgment criteria for potentially inappropriate medication (PIM)in the elderly ,and to provide reference for clinical selection of appropriate PIM evaluation tools for the elderly. METHODS From the aspects of applicable age ,content and scale characteristics ,five commonly used PIM judgment criteria for the elderly at home and abroad were analyzed and compared ,namely Beer ’s criteria ,STOPP/START v 2 criteria,ACOVE 3 criteria,PIM-Check criteria and“Judgment Criteria for Potentially Inappropriate Medication for Chinese Elderly ”(Chinese criteria ). RESULTS The five standards both overlapped and focused in terms of scale characteristics. In each study ,the incidence of PIM was different according to different standards. Proton pump inhibitors ,diuretics,non-steroidal anti-inflammatory drugs and anticoagulants were the most frequently occurring PIM drugs for the elderly. CONCLUSIONS Combining with the specific conditions of patients and fully considering the benefits and risks of treatment ,rational selection and combination of five PIM judgment criteria ,and necessary supplements to my country ’s PIM judgment criteria ,will help clinicians and pharmacists to improve the efficacy and safety of the medication in the elderly patients.
期刊: 2022年第33卷第09期
作者: 廖雅慧,郎驿天,林燕,刘晓琰
AUTHORS: LIAO Yahui,LANG Yitian,LIN Yan,LIU Xiaoyan
关键字: 潜在不适当用药;老年人;判断标准;有效性;安全性
KEYWORDS: potentially inappropriate medication ;the elderly ;judgment criteria ;efficacy;safety
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