目的：为晚期癌症、中重度疼痛镇痛药物的合理使用提供参考。方法：从某三甲医院的信息管理系统中提取2012－2014

年麻醉药品和第一类精神药品的相关数据，对使用数量和销售金额、用药频度（DDDs）等进行统计分析。结果：该院2012－2014

年麻醉药品和第一类精神药品的整体使用数量基本持平，各年的销售金额分别为1 566 289.92、1 525 220.23、1 531 277.44 元。盐

酸吗啡片的销售金额增长最快，2013、2014 年分别比前一年增长了89.78％和142.81％，其余药品大多为负增长。盐酸吗啡缓释片

的DDDs 3 年均排名第1 且逐年递增，从2012 年的26 848.00 增加至2014 年的47 158.00。结论：该院麻醉药品和第一类精神药品

用药基本符合规范，但仍然需要严格监管，使之更加安全、有效地应用于临床。

OBJECTIVE：To provide reference for rational use of analgesic drugs for advanced cancer，moderate to severe

pain. METHODS：The data of narcotic drugs and first type psychotropic drugs were collected from hospital information system of a

third grade class A hospital during 2012-2014，and then analyzed in respects of amount，consumption sum and DDDs，etc. RESULTS：

The amount of narcotic drugs and first type psychotropic drugs kept stable basically，and the consumption sum of them

during 2012-2014 was 1 566 289.92 yuan，1 525 220.23 yuan and 1 531 277.44 yuan. The consumption sum of Morphine hydrochloride

tablet increased the fastest，increasing by 89.78％ in 2013 and 142.81％ in 2014，compared with the year before；those of other

drugs had negative growth rate. DDDs of Morphine hydrochloride sustained-release tablets were the highest among all the narcotics

and first type psychotropic drugs and increased year by year，increasing from 26 848.00 in 2012 to 47 158.00 in 2014. CONCLUSIONS：

The use of narcotic drugs and first type psychotropic drugs conform to the specifications，but they still need strict supervision

to promote safe and effective use of them in the clinic.