江苏省某三级公立医院治疗高血压和糖尿病的原研药和仿制药利用分析
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篇名: 江苏省某三级公立医院治疗高血压和糖尿病的原研药和仿制药利用分析
TITLE:
摘要: 目的:为仿制药替代原研药的经济效益提供证据支持,提出促进仿制药使用的政策建议。方法:选取江苏省某三级公立医院治疗高血压和糖尿病的12种既有原研药又有仿制药的药物,逐季度分析2017-2018年原研药和仿制药使用量占比、使用金额占比、价格比和2018年仿制药替代原研药的潜在费用节省率。结果:2017年第1季度-2018年第4季度,原研药、仿制药使用数量占比分别由24.53%上升至39.12%、75.47%下降至60.88%,使用金额占比分别由39.45%上升至61.47%、60.55%下降至38.53%,仿制药与原研药价格比从0.50下降到0.40。在疗效一致的条件下,2018年仿制药替代原研药潜在可节约费用62.21万元,费用节省率为47.65%。结论:仿制药替代原研药具有降低药品支出的作用,但该院仿制药使用或金额占比却逐渐下降。因此,有必要加快仿制药一致性评价的进程及临床等效研究,加大仿制药处方及合理使用的教育宣传,以提高医患对仿制药质量和疗效的认同,配合鼓励仿制药采购及使用的集中采购政策,促进仿制药利用以节约药品支出。
ABSTRACT: OBJECTIVE: To provide evidence support for the economic benefits of generic drugs as substitutes for original drugs, and to provide suggestions for promoting the use of generic drugs. METHODS: Twelve kinds of drugs with both original and generic versions for treating hypertension and diabetes were selected from a tertiary public hospital in Jiangsu province. The proportion of usage quantity, the ratio of amount, price ratio were analyzed quarterly during 2017-2018. RESULTS: From the first quarter of 2017 to the fourth quarter of 2018, the ratio of quantity of original drugs increased from 24.53% to 39.12%, while that of generic drugs decreased from 75.47% to 60.88%; the ratio of amount of original drugs increased from 39.45% to 61.47%, while that of generic drugs decreased from 60.55% to 38.53%; the price ratio of generic drug to original drug decreased from 0.50 to 0.40. With the same efficacy, the cost of generic drugs replacing original drugs in 2018 could save 622,100 yuan, and the cost savings rate could be 47.65%. CONCLUSIONS: Drug expenditure could be reduced by substituting original drug with generics, but the useage quantity and amount ratio of generic drug in this hospital is gradually declining. So, in order to save drug experditure, it is necessary to speed up the process of conformity evaluation and clinical equivalence study of generic drugs, increase the education and publicity of generic prescriptions and rational use, so as to improve doctors’ and patients’ recognition of the quality and efficacy of generic drugs, cooperate with the centralized procurement policy to encourage the purchase and use of generic drugs.
期刊: 2019年第30卷第21期
作者: 唐媛媛,陈敬,李歆
AUTHORS: TANG Yuanyuan,CHEN Jing,LI Xin
关键字: 高血压;糖尿病;仿制药;原研药;使用数量;使用金额;价格比;费用节省
KEYWORDS: Hypertension; Diabetes; Generic drug; Original drug; Usage quantity; Usage amount; Price ratio; Cost saving
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