多指标正交试验优化大黄的湿纸煨制工艺
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篇名: 多指标正交试验优化大黄的湿纸煨制工艺
TITLE:
摘要: 目的:优化大黄的湿纸煨制工艺。方法:以煨制后大黄的外观性状、浸出物含量、总蒽醌含量、游离蒽醌含量、结合蒽醌含量、番泻苷A+番泻苷B含量等多个指标的加权综合评分值为考察指标,采用L9(34)正交试验对用纸量、煨制时间、 煨制温度3个因素进行考察,优化大黄的湿纸煨制工艺,并进行验证试验。结果:优化的大黄煨制工艺为每100 g大黄用纸12 g包裹、120 ℃炮制2 h。验证试验及中试试验结果显示,煨制后大黄的综合评分均值分别为84.99(RSD<2.0%,n=3)、85.06(RSD<2.5%,n=3)。结论:优化后的大黄煨制工艺简便易行,重复性和可操作性好,本研究为煨大黄的规范化制备奠定了技术基础。
ABSTRACT: OBJECTIVE: To optimize the wet paper roasting technology of Rheum palmatum. METHODS: Weighted comprehensive score composed of external properties of R. palmatum roasting with wet paper, the content of extract, total content of anthraquinone, free anthraquinones, conjugated anthraquinone and sennoside A+sennoside B, which were used as investigation indexes. L9 (34) orthogonal test was adopted to investigate the three factors as the amount of paper, roasting time and roasting temperature, and optimized wet paper roasting technology of R. palmatum. Validation test was conducted. RESULTS: The optimal roasting technology was as follows as 100 g R. palmatum covered with 12 g paper, processing at 120 ℃, for 2 h. The results of validation test and pilot test showed the average comprehensive scores of roasted R. palmatum were 84.99 (RSD<2.0%, n=3) and 85.06 (RSD<2.5%, n=3), respectively. CONCLUSIONS: The optimal processing technology is simple and convenient with good reproducibility and operability. It lays a technical foundation for the standardized preparation of stewed R. palmatum.
期刊: 2018年第29卷第7期
作者: 张志,李听弦,姚楠,谢婧,王光忠
AUTHORS: ZHANG Zhi,LI Tingxian,YAO Nan,XIE Jing,WANG Guangzhong
关键字: 大黄;湿纸煨制工艺;正交试验;多指标;加权评分法
KEYWORDS: Rheum palmatum; Wet paper roasting technology; Orthogonal test; Multi-index; Weighted scoring method
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