《儿科阿奇霉素注射使用的快速建议指南》实施方案介绍
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篇名: 《儿科阿奇霉素注射使用的快速建议指南》实施方案介绍
TITLE:
摘要: 目的:规范和指导指南制订流程,保障科学和循证地完成《儿科阿奇霉素注射使用的快速建议指南》的制订。方法:介绍本指南实施方案,包括制订机构和指南注册,项目组的组建,指南适用范围,利益声明和资金资助,临床问题和结局指标的确定,循证证据的检索与处理,患者偏好和价值观调查,经济学分析,推荐意见的形成、外审和批准,指南发布、传播、更新等过程。结果:按本实施方案已完成指南指导委员会、专家组、秘书组的组建和指南的注册(注册号:IPGRP-2016CN013),形成了适应证、用法用量、不良反应及护理、特殊人群用药等临床问题以及有效性和安全性结局指标;并已于2017年末发布推荐意见,拟于2018年发表本指南全文及解读,计划于2022年对本指南进行更新。结论:本实施方案提供了方法学和纲要性的指导,可为科学和循证地制订指南提供依据,进而促进临床合理用药。
ABSTRACT: OBJECTIVE: To standardize and guide the formulation process of guideline and guarantee the evidence-based formulation of Rapid Advice Guideline for Intravenous Azithromycin in Pediatrics scientifically. METHODS: The protocol of the guideline was introduced, such as guideline-making institution and registration, establishment of project group, scope of application, declaration of interest and funding support, identification of the clinical issues and outcome indexes, evidence retrieval and processing, invastigation of patients preferences and values, economics analysis, development of recommendation, external review and approval, guideline release, dissemination and update, etc. RESULTS: The construction of guidance committee, expert group and secretarial group, the registration (registration number:IPGRP-2016CN013) of the guideline had been achieved according to this protocol; clinical issues (such as indications, usage and dosage, ADR and treatment, drug use in special population) and effectiveness, safety outcome indexes had been formed. The recommendations have been issued by the end of 2017; the full text and interpretation of the guideline will be published in 2018; the guideline will be updated in 2022. CONCLUSIONS: This protocol provides the methodological and programmatic guide and provides reference for evidence-based formulation of the guideline scientifically so as to promote clinical rational drug use.
期刊: 2018年第29卷第4期
作者: 周鹏翔,梁舒瑶,翟所迪
AUTHORS: ZHOU Pengxiang,LIANG Shuyao,ZHAI Suodi
关键字: 阿奇霉素;儿科;注射剂;快速建议指南;指南实施方案
KEYWORDS: Azithromycin; Pediatrics; Injection; Rapid advice guideline; Protocol
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