某综合医院骨科住院患者盐酸克林霉素注射剂使用合理性评价
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篇名: 某综合医院骨科住院患者盐酸克林霉素注射剂使用合理性评价
TITLE:
摘要: 目的:为盐酸克林霉素注射剂的临床合理使用提供依据。方法:回顾性调查分析某“三甲”综合医院2013-2015年骨科住院患者使用盐酸克林霉素注射剂的情况,并制订合理性评价标准,对其用药合理性进行评价。结果:共189例骨科住院患者使用了盐酸克林霉素注射剂,用药不合理的患者有152例,其中治疗性用药不合理的有16例,预防性用药不合理的有136例;不合理用药类型主要为用法用量不适宜(86.18%)、遴选药物不适宜(44.74%)和药物更换不适宜(15.79%)。有2例患者发生药品不良事件,分别为皮疹和恶心,经停药并对症处理后均好转,其中1例用药不合理。结论:盐酸克林霉素注射剂在骨科的应用存在不合理现象,需进一步规范用药行为,保障用药安全有效。
ABSTRACT: OBJECTIVE: To provide reference for rational use of Clindamycin hydrochloride injection. METHODS: The utilization of Clindamycin hydrochloride injection in orthopedic inpatients of a third grade class A general hospital during 2013-2015 was analyzed and investigated retrospectively. The rationality evaluation standard was formulated to evaluate the rationality of drug use in those patients. RESULTS: A total of 189 orthopedic inpatients received Clindamycin hydrochloride injection, and there were 152 cases of irrational drug use among which there were 16 cases of irrational therapeutic drug use and 136 cases of irrational prophylactic drug use. Irrational drug use mainly included irrational usage and dosage (86.18%), irrational drug selection (44.74%) and irrational drug replacement (15.79%). Two patients suffered from ADE, i.e. rash and nausea. After drug withdrawal and symptomatic treatment, the symptoms were improved, but irrational drug use was found in one case. CONCLUSIONS: The utilization of Clindamycin hydrochloride injection is irrational in orthopedic department. It is necessary to further standardize medication behavior and guarantee the safety and effectiveness of drug use.
期刊: 2017年第28卷第29期
作者: 颜铭,滕韦卫,崔岚
AUTHORS: YAN Ming,TENG Weiwei,CUI Lan
关键字: 盐酸克林霉素注射剂;骨科;住院患者;合理用药
KEYWORDS: Clindamycin hydrochloride injection; Orthopedics; Inpatients; Rational drug use
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