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药学服务对糖尿病患者血糖控制效果和用药依从性的影响
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| 篇名： | 药学服务对糖尿病患者血糖控制效果和用药依从性的影响 |
| TITLE： | |
| 摘要： | 目的：探讨药学服务对糖尿病患者血糖控制效果和用药依从性的影响。方法：选取2015年4－9月我院糖尿病出院患者92例，按随机数字表法分为对照组和干预组，各46例。两组患者均给予氯磺丙脲片+二甲双胍格列本脲片（Ⅰ）联合治疗，治疗时间均为3个月；干预组患者在此基础上行用药教育、电话随访等药学服务。比较治疗前后两组患者糖化血红蛋白及血糖水平、用药依从性的差异。结果：治疗前，两组患者糖化血红蛋白及血糖水平、用药依从性比较，差异均无统计学意义（P＞0.05）。治疗后，两组患者糖化血红蛋白及血糖水平均显著下降，且干预组显著低于对照组；年龄＜60岁患者血糖控制效果优于年龄≥60岁患者，差异均有统计学意义（P＜0.05）。治疗1个月后，两组用药依从性佳比例均显著提高，且干预组显著高于对照组；治疗3个月后，两组用药依从性佳比例均显著高于同组治疗前和治疗1个月后，且干预组显著高于对照组；年龄＜60岁患者用药依从性改善程度优于年龄≥60岁患者，差异均有统计学意义（P＜0.05）。结论：药学服务有助于糖尿病患者的血糖控制，并可提高其用药依从性，尤其对年龄＜60岁患者的效果更好。 |
| ABSTRACT： | OBJECTIVE： To explore the effects of pharmaceutical care on blood glucose control and medication compliance in patients with diabetes mellitus. METHODS： Nighty-two discharged patients with diabetes mellitus in our hospital from Apr. to Sept. 2015 were divided into intervention group and control group by random number table method， with 46 cases in each group. Both groups were given Chlorpropamide tablets+Metformin glibenclamide tablets （Ⅰ） for 3 months； intervention group additionally received pharmaceutical care as medication education， telephone follow-up， etc. The levels of glycosylated hemoglobin and blood glucose， medication compliance were compared between 2 groups before and after treatment. RESULTS： Before treatment， there was no statistical significance in the levels of glycosylated hemoglobin and blood glucose， or medication compliance between 2 groups （P＞0.05）. After treatment， the levels of glycosylated hemoglobin and blood glucose in 2 groups were significantly decreased， and the intervention group was significantly lower than control group； the effects of blood glucose control in patients younger than 60 years old were better than in patients older than 60 years old， with statistical significance （P＜0.05）. After one month of treatment， the proportion of good medication compliance were increased significantly in 2 groups， and the intervention group was significantly higher than control group. After 3 months of treatment， the proportion of good medication compliance in 2 groups were significantly higher than before treatment， and 1 month after treatment， while the intervention group was significantly higher than control group. The improvement of medication compliance in patients younger than 60 years old was better than in patients older than 60 years old， with statistical significance （P＜0.05）. CONCLUSIONS： Pharmaceutical care contributes to blood glucose control and improves the medication compliance， especially for those younger than 60 years old. |
| 期刊： | 2017年第28卷第11期 |
| 作者： | 韩冰，杨其莲，喻轶群 |
| AUTHORS： | HAN Bing，YANG Qilian，YU Yiqun |
| 关键字： | 糖尿病；药学服务；血糖控制；用药依从性 |
| KEYWORDS： | Diabetes mellitus； Pharmaceutical care； Blood glucose control； Medication compliance |
| 阅读数： | 581 次 |
| 本月下载数： | 38 次 |
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