均匀设计法优化藏药多血康提取工艺
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篇名: 均匀设计法优化藏药多血康提取工艺
TITLE:
摘要: 目的:优化多血康的提取工艺。方法:以红景天苷、没食子酸含量及出膏率的综合评分为指标,采用U6(63)均匀设计法优化多血康提取工艺中的料液比、乙醇体积分数及提取时间,再优化提取次数,并进行验证试验。结果:最优提取工艺为采用50%乙醇,料液比1 ∶ 14,浸泡1.5 h,回流提取1 h并重复2次;3次试验平均出膏率为50.18%,红景天苷和没食子酸含量分别为1.82、16.54 mg/g(RSD≤0.84%,n=3)。结论:优化的多血康提取工艺合理、简单、可行。
ABSTRACT: OBJECTIVE: To optimize the extraction technology of Duoxuekang. METHODS: Using comprehensive score of salidroside, gallic acid content and extraction yield as indexes, U6(63) uniform design was designed to optimize the liquid-solid ratio, ethanol volume fraction and extraction time of Duoxuekang, then optimize extraction times, and verification test was conducted. RESULTS: The optimal extraction technology was as follows as 50% ethanol, liquid-solid ratio of 1 ∶ 14, soaking time of 1.5 h, reflux extraction for 1 h and repeated twice; the average extraction yield in 3 tests was 50.18%, contents of salidroside and gallic acid were 1.82 mg/g, 16.54 mg/g (RSD≤0.84%, n=3). CONCLUSIONS: The optimized extraction technology for Duoxuekang is reasonable, simple and feasible.
期刊: 2017年第28卷第10期
作者: 吕秀梅,王静,赵可惠,张静,赖先荣,范刚,张艺,更藏加
AUTHORS: LYU Xiumei,WANG Jing,ZHAO Kehui,ZHANG Jing,LAI Xianrong,FAN Gang,ZHANG Yi,GENG Zangjia
关键字: 藏药;多血康;均匀设计法;红景天苷;没食子酸;含量;提取;工艺优化
KEYWORDS: Tibetan medicine; Duoxuekang; Uniform design; Salidroside; Gallic acid; Content; Extraction; Technology optimization
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