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从不同决策主体角度测算分析药物性肝损伤的相关成本
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| 篇名： | 从不同决策主体角度测算分析药物性肝损伤的相关成本 |
| TITLE： | |
| 摘要： | 目的：从不同决策主体角度测算分析药物性肝损伤（DILI）的相关成本，为降低DILI相关成本、完善医保体系以及实现卫生资源有效配置提供参考依据。方法：采用回顾性研究方法，随机选取河南省4家医院病案管理系统中2014年6月－2015年6月第一诊断为DILI，且治疗结果为痊愈或者好转的住院患者60例作为研究对象，统计DILI患者的人口学特征、临床特征和DILI相关成本，并从不同决策主体（患者、全社会和医保支付方）角度对成本构成情况进行分析。结果：60例患者的直接医疗成本总额为584 113.05元，直接非医疗成本总额为31 093.15元，间接成本总额为169 379.95元；患者所承担的DILI相关成本总额为616 296.38元；全社会所承担的DILI相关成本总额为784 586.15元；医保支付方所承担的DILI相关成本总额为168 289.77元。结论：DILI给患者及全社会带来了严重的经济损失，应引起社会各界的关注和重视。本研究结果为减轻患者医疗负担和完善医保制度提供了参考依据，有利于医疗资源的优化配置。 |
| ABSTRACT： | OBJECTIVE： To measure and analysis the related costs of drug-induced liver injury （DILI） from different decision makers， and to provide reference for reducing related costs of DILI， improving medical insurance system and realizing effective health resource distribution. METHODS： In retrospective study， 60 cured or recovered DILI inpatients were randomly selected as subjects from medical record management system of 4 hospitals in Henan province during Jun. 2014-Jun. 2015. Demographic characteristic， clinical characteristic and related cost of DILI were analyzed retrospectively and the cost structure was also analyzed from different decison makers （patient， society， medical insurance payer）. RESULTS： The total direct medical cost of 60 cases was 584 113.05 yuan， and total direct non-medical cost was 31 093.15 yuan and total indirect cost was 169 379.95 yuan. The total cost of DILI offered by patients was 616 296.38 yuan； the total cost of DILI offered by society was 784 586.15 yuan； the total cost of DILI offered by medical insurance was 168 289.77 yuan. CONCLUSIONS： DILI results in serious economic damage for patients and society， deserving attracting extensive attention worldwide. The study provide reference for reducing patient’s medical burden and improving medical insurance system， and contribute to optimize medical resource distribution. |
| 期刊： | 2017年第28卷第8期 |
| 作者： | 杨翠翠，张丽霄，秦静静，张丽珍，杜书章 |
| AUTHORS： | YANG Cuicui，ZHANG Lixiao，QIN Jingjing，ZHANG Lizhen，DU Shuzhang |
| 关键字： | 药物性肝损伤；决策主体；成本测算；药物经济学；医保 |
| KEYWORDS： | Drug-induced liver injury； Decision maker； Cost calculation； Pharmacoeconomics； Medical insurance |
| 阅读数： | 267 次 |
| 本月下载数： | 6 次 |
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