复方雪莲烧伤膏治疗深Ⅱ度烧伤的临床观察
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篇名: 复方雪莲烧伤膏治疗深Ⅱ度烧伤的临床观察
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摘要: 目的:探讨复方雪莲烧伤膏治疗深Ⅱ度烧伤患者的效果及安全性。方法:采用同体对照法,选取80例深Ⅱ度烧伤患者四肢上对称或相邻部位的2处烧伤创面(均为深Ⅱ度烧伤,面积约为10 cm×10 cm),分为治疗区和对照区。治疗区给予复方雪莲烧伤膏治疗,对照区给予磺胺嘧啶银乳膏治疗。观察2个区域创面愈合时间、患者换药疼痛程度、渗液量、创面感染率、瘢痕发生率及不良反应发生情况。结果:治疗区创面愈合时间[(18.7±3.6)d]明显短于对照区[(23.8±3.1)d],差异有统计学意义(P<0.05);治疗期间,治疗区换药剧痛难忍和重度疼痛的患者比例、渗液量和创面瘢痕发生率均明显低于或少于对照区,换药轻度疼痛的患者比例明显高于对照区,差异均有统计学意义(P<0.05);而两者换药中度疼痛和无痛的患者比例、创面感染率比较,差异均无统计学意义(P>0.05)。80例患者均未见明显不良反应。结论:复方雪莲烧伤膏治疗深Ⅱ度烧伤患者,可降低其换药的疼痛程度,减少伤口渗液量,促进创面愈合,减少瘢痕的发生,且安全性良好。
ABSTRACT: OBJECTIVE: To investigate the effects and safety of Compound xuelian burning wound ointment in the treatment ofⅡdegree deep burn. METHODS: Using consubstantial control method, 2 burn wounds (Ⅱdegree deep burn, about 10 cm×10 cm) selected from symmetric or adjacent part of extremities in 80 patients withⅡdegree deep burn were divided into treatment area and control area. Treatment area was given Compound xuelian burning wound ointment, and control area was given Sulfadiazine silver cream. Healing time, degree of pain due to dressing change, the amount of infiltration liquid, wound infection rate, the incidence of scar formation and the incidence of ADR were observed. RESULTS: The healing time of wound in treatment area was significantly shorter than in control group [(18.7±3.6)d vs. (23.8±3.1)d], with statistical significance (P<0.05). During treatment, the proportion of patients suffering from acute pain and severe pain due to dressing change in treatment area, the amount of infiltration liquid and the incidence of scar formation were significantly lower or less than in control area; the proportion of patients suffering from mild pain due to dressing change in treatment area was significantly higher than in control area, with statistical significance (P<0.05). There was no statistical significance in the proportion of patients suffering from moderate pain and indolence due to dressing change, the incidence of wound infection between treatment area and control area (P>0.05). No obvious ADR was found in 80 patients. CONCLUSIONS: Compound xuelian burning wound ointment in the treatment of Ⅱdegree deep burn can relieve the degree of pain due to dressing change, control the amount of infiltration liquid, promote wound healing and reduce the occurrence of scar with good safety.
期刊: 2016年第27卷第35期
作者: 黄崇根,顾在秋,严炯,储国平
AUTHORS: HUANG Chonggen,GU Zaiqiu,YAN Jiong,CHU Guoping
关键字: 复方雪莲烧伤膏;深Ⅱ度烧伤;创面愈合;渗液量;感染;瘢痕
KEYWORDS: Compound xuelian burning wound ointment; Ⅱdegree deep burn; Wound healing; Amount of infiltration liquid; Infection; Scar
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