益母草膏对比丹莪妇康煎膏治疗原发性痛经的临床观察
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篇名: | 益母草膏对比丹莪妇康煎膏治疗原发性痛经的临床观察 |
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摘要: | 目的:比较益母草膏与丹莪妇康煎膏治疗原发性痛经的疗效和安全性。方法: 80例原发性痛经患者随机分为益母草膏组(40例)和丹莪妇康煎膏组(40例)。益母草膏组患者给予益母草膏10 g,口服,每日2次。丹莪妇康煎膏组患者给予丹莪妇康煎膏10 g,口服,每日2次。两组患者均自月经前第10天开始用药,连用10 d为1个疗程,共治疗6个疗程。用药期间嘱咐患者不吃冷饮冷食,使用温水洗脸洗脚,有条件者每晚用热水泡脚,注意小腹部和腿部的保暖。若患者行经时疼痛难忍,给予布洛芬缓释胶囊0.3 g,口服,每日2次。观察两组患者的临床疗效,治疗前后症状积分(痛经程度、小腹胀痛、腰骶酸痛)、痛经持续时间、止痛药服用次数及不良反应发生情况。结果:两组患者总有效率、不良反应发生率比较,差异均无统计学意义(P>0.05)。治疗前,两组患者痛经程度积分、小腹胀痛积分、腰骶酸痛积分、痛经持续时间及止痛药服用次数比较,差异均无统计学意义(P>0.05)。治疗后,两组患者痛经程度积分、小腹胀痛积分、腰骶酸痛积分均显著低于同组治疗前,且丹莪妇康煎膏组低于益母草膏组,差异均有统计学意义(P<0.05);痛经持续时间及止痛药服用次数均显著低于同组治疗前,差异有统计学意义(P<0.05),但两组间比较差异无统计学意义(P>0.05)。结论:益母草膏与丹莪妇康煎膏治疗原发性痛经的疗效和安全性均较好,但在改善临床症状方面丹莪妇康煎膏优于益母草膏。 |
ABSTRACT: | OBJECTIVE: To compare the efficacy and safety of Leonurus artemisia cream and Dan’e fukang cream in the treatment of primary dysmenorrhea. METHODS: 80 patients with primary dysmenorrheal were randomly divided into L. artemisia cream group (40 cases) and Dan’e fukang cream group (40 cases). L. artemisia cream group received L. artemisia cream 10 g, orally, twice a day. Dan’e fukang cream group received Dan’e fukang cream 10 g, orally, twice a day. The treatment was stated before 10 days of menstruation. 10 days was regarded as 1 treatment course, and it lasted for 6 courses. Cold drink and food were forbid during medication, washing face and feet with warm water, soaking feet with hot water if they can, paying attention to keep the lower abdomen and legs warm. If patients felt unbearable pain in menstruation, 0.3 g Ibuprofen sustained release capsule was given, orally twice a day. Clinical efficacy, symptom score (dysmenorrhea degree,abdominal pain,lumbosacral pain)before and after treatment, dysmenorrhea duration, frequency of taking painkillers and the incidence of adverse reactions in 2 groups were observed. RESULTS: There were no significant differences in the total effective rate and the incidence of adverse reactions in 2 groups (P>0.05). Before treatment, there were no significant differences in dysmenorrhea degree, abdominal pain, lumbosacral pain score, dysmenorrheal duration and frequency of taking painkillers in 2 groups (P>0.05). After treatment, the dysmenorrhea degree, abdominal pain, lumbosacral pain score in 2 groups were significantly lower than before, and Dan’e fukang cream group was lower than L. artemisia cream group with statistical sighificance(P<0.05),and dysmenorrheal duration and frequency of taking painkillers were significantly lower than before, with statistical significance (P<0.05), while there was no significant difference in 2 groups (P>0.05). CONCLUSIONS: Both L. artemisia cream and Dan’e fukang cream have good efficacy and safety in the treatment of primary dysmenorrhea, while Dan’e fukang cream is superior to L. artemisia cream in terms of improving clinical symptoms. |
期刊: | 2016年第27卷第30期 |
作者: | 李明慧,芦小娟,张亚凤,刘天舒 |
AUTHORS: | LI Minghui,LU Xiaojuan,ZHANG Yafeng,LIU Tianshu |
关键字: | 益母草膏;丹莪妇康煎膏;原发性痛经;疗效;安全性 |
KEYWORDS: | Leonurus artemisia cream; Dan’e fukang cream; Primary dysmenorrhea; Efficacy; Safety |
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