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双黄连口服液联合头孢呋辛酯治疗细菌性呼吸道感染的临床观察
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| 篇名： | 双黄连口服液联合头孢呋辛酯治疗细菌性呼吸道感染的临床观察 |
| TITLE： | |
| 摘要： | 目的：观察双黄连口服液联合头孢呋辛酯治疗细菌性呼吸道感染的临床疗效和安全性。方法：184例细菌性呼吸道感染患者随机均分为试验组和对照组。试验组患者给予头孢呋辛酯片250 mg，口服，每日2次+双黄连口服液20 ml，口服，每日3次；对照组患者仅给予头孢呋辛酯片（用法用量同试验组）。两组疗程均为2周。观察两组患者治疗前后咳嗽持续时间、体温恢复时间和流涕消失时间，细菌清除率和临床疗效，并记录不良反应发生情况。结果：治疗后，试验组患者总有效率显著高于对照组，咳嗽持续时间、体温恢复时间和流涕消失时间均显著短于对照组，差异均有统计学意义（P＜0.05）；两组患者细菌清除率、不良反应发生率比较，差异均无统计学意义（P＞0.05）。结论：双黄连口服液联合头孢呋辛酯相比单用头孢呋辛酯治疗细菌性呼吸道感染疗效更好，且安全性相当。 |
| ABSTRACT： | OBJECTIVE：To observe the clinical efficacy and safety of Shuanghuanglian oral liquid combined with cefuroxime axetil in the treatment of bacterial respiratory tract infection. METHODS：184 patients with bacterial respiratory tract infection were randomly divided into test group and control group. Test group was orally given 250 mg Cefuroxime axetil tablet， twice a day+20 ml Shuanghuanglian oral liquid，3 times a day. Control group was only given Cefuroxime axetil tablet （the same dosage as test group）. The treatment course for 2 groups was 2 weeks. The cough duration， body temperature recovery time and runny nose disappearing time before and after treatment and bacterial clearance rate in 2 groups were observed， clinical efficacy and incidence of adverse reactions were recorded. RESULTS： After treatment， the total effective rate in test group was significantly higher than control group， cough duration， body temperature recovery time and runny nose disappearing time were significantly shorter than control group， the differences were statistically significant（P＜0.05）； and there were no significant differences in the bacterial clearance rate and incidence of adverse reactions（P＞0.05）. CONCLUSIONS：The efficacy of Shuanghuanglian oral liquid combined with cefuroxime axetil is superior to cefuroxime axetil alone in the treatment of bacterial respiratory infections， with similar safety. |
| 期刊： | 2016年第27卷第12期 |
| 作者： | 吴潇，祁明浩 |
| AUTHORS： | WU Xiao，QI Minghao |
| 关键字： | 双黄连口服液；头孢呋辛酯；细菌性呼吸道感染；疗效；安全性 |
| KEYWORDS： | Shuanghuanglian oral liquid； Cefuroxime axetil； Bacterial respiratory infection； Efficacy； Safety |
| 阅读数： | 773 次 |
| 本月下载数： | 1 次 |
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