附子逍遥散配合快速针刺法治疗抑郁症的临床观察
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篇名: 附子逍遥散配合快速针刺法治疗抑郁症的临床观察
TITLE:
摘要: 目的:观察附子逍遥散配合快速针刺法治疗抑郁症的临床疗效及安全性。方法:将80例抑郁症患者按随机数字表法分为观察组和对照组,各40例。对照组患者给予帕罗西汀20 mg,qd;观察组患者给予附子逍遥散,水煎成200 ml,每日分3次服用,配合快速针刺法治疗。两组患者均6 d为1个疗程,共治疗6个疗程。观察两组患者临床疗效、治疗前后汉密尔顿抑郁量表(HAMD)评分、血清5-羟色胺(5-HT)含量和Asberg副作用量表(SERS)评分。结果:观察组患者有效率为82.5%,显著高于对照组患者的62.5%,差异有统计学意义(P<0.05);治疗后两组患者的HAMD评分均较治疗前显著下降,且观察组低于对照组,差异有统计学意义(P<0.05);两组患者血清5-HT含量治疗后均有显著升高,与治疗前比较差异均有统计学意义(P<0.05),但组间比较差异无统计学意义(P>0.05)。治疗后观察组患者SERS评分均显著低于对照组,差异有统计学意义(P<0.05)。结论:附子逍遥散配合快速针刺法治疗抑郁症患者疗效显著,且安全性较好。
ABSTRACT: OBJECTIVE: To observe the clinical efficacy and safety of Fuzi xiaoyao powder combined with rapid acupuncture in the treatment of depression. METHODS: A total of 80 depression patients were randomly divided into observation group and control group, with 40 cases in each group. Control group was treated with paroxetine 20 mg, qd; observation group was given Fuzi xiaoyao powder 200 ml, one dose a day, at third, combined with rapid acupuncture. Two groups of patients for 6 days for a course of treatment, a total of 6 courses of treatment. Clinical efficacy, HAMD, serum content of 5-HT and Asberg side reaction scale (SERS) were observed in 2 groups. RESULTS: The effective rate of observation group was 82.5%, which was significantly higher than 62.5% of control group, with statistical significance (P<0.05); after treatment, HAMD of 2 groups decreased significantly, and the observation group was lower than the control group, with statistical significance (P<0.05). Compared with before treatment, erum content of 5-HT increased significantly in 2 groups after treatment, with statistical significance (P<0.05); there was no statistical significance between 2 groups (P>0.05). After treatment, SERS of observation group was significantly lower than that of control group, with statistical significance (P<0.05). CONCLUSIONS: Fuzhi xiaoyao powder combined with rapid acupuncture show certain therapeutic efficacy in the treatment of depression,with good safety
期刊: 2016年第27卷第11期
作者: 周秀芳,胡捷,张迎梅,陈河燕
AUTHORS: ZHOU Xiufang,HU Jie,ZHANG Yingmei,CHEN Heyan
关键字: 附子逍遥散;快速针刺法;抑郁症
KEYWORDS: Fuzhi xiaoyao powder; Rapid acupuncture; Depression
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