健康效用评价的影响因素分析
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篇名: 健康效用评价的影响因素分析
TITLE:
摘要: 目的:分析健康效用评价的影响因素,为关注亚组人群健康偏好的卫生决策者、制药企业等提供参考,并为成本-效用分析中选择合适人群来测量健康偏好提供依据。方法:选取贵州省内年满16周岁的城市及农村人群各240例作为受访者,采用时间权衡法直接测量欧洲五维健康量表部分状态的效用值,构建计量模型,分析受访者年龄、性别、民族、受教育程度、医疗保险、自身健康状况等因素对所有健康状态及轻度、中度、重度状态的影响。结果:共发放481份问卷,回收有效问卷467份,有效率为97.09%。女性、少数民族、年龄较大、有医疗保险、患有经医师诊断的慢性病或过去1个月健康状况较差的受访者给予健康状态效用较高的评价值,而没有配偶或与配偶分居、受教育水平偏低的受访者则给予较低的评价值。结论:受访者的个人特征对其在评价健康效用时存在显著影响,相关研究应根据需要选择合适的偏好来源。
ABSTRACT: OBJECTIVE: To analyze influential factors of health utility evaluation, so as to provide reference for policy-makers, pharmaceutical companies and other relevant organizations prioritized in improving the quality of life for specific groups of people, and to provide supports to researchers to find the appropriate people to elicit the preferences for health states. METHODS: 240 urban respondents and 240 country respondents aged more than 16 were selected from Guizhou province. Utility values for a subset of health states defined by the EQ-5D descriptive system were directly elicited by applying Time trade-off technique. Linear regression models were used to estimate the effect of individual characteristics as age, gender, race, educational level, insurance status, health conditions on all health states, mild, medium and severe states. RESULTS: A total of 481 questionnaires were sent out and 467 valid questionnaires were collected with the effective rate of 97.09%.  Higher valuations were given by respondents who were the female, belonging to the minority group, elder person, with health insurance, with chronic disease diagnosed by the doctor, or with a poor health status at the past month. However, the respondents living themselves, with low educational level assigned lower valuations. CONCLUSIONS: Utilities for health states are influenced by respondent’s characteristics significantly. It is very important for the research to choose the appropriate people to elicit the preferences for health states.
期刊: 2016年第27卷第11期
作者: 伍红艳,刘国恩,官海静
AUTHORS: WU Hongyan,LIU Guoen,GUAN Haijing
关键字: 健康效用;时间权衡法;欧洲五维健康量表;影响因素;质量调整生命年
KEYWORDS: Health utility; Time trade-off; EQ-5D; Influential factors; QALYs
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