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西安地区36家二级医院2015年第2季度抗菌药物应用分析
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| 篇名： | 西安地区36家二级医院2015年第2季度抗菌药物应用分析 |
| TITLE： | |
| 摘要： | 目的：了解抗菌药物临床应用专项整治活动的成效，为抗菌药物合理使用提供参考。方法：参照2013年《全国抗菌药物临床应用专项整治活动方案》中规定的抗菌药物合理应用指标，对西安地区36家二级医院2015年第2季度的抗菌药物应用指标和抗菌药物种类、销售金额、用药频度（DDDs）及日均费用（DDC）等进行回顾性分析。结果：西安地区36家二级医院抗菌药物应用主要指标均达标的仅有3家（占8.33％），住院患者抗菌药物使用达标率为91.66％，住院患者抗菌药物使用强度达标率为55.56％，门诊抗菌药物处方比例达标率为50.00％，急诊抗菌药物处方比例达标率为77.78％，Ⅰ类切口手术抗菌药物预防使用率为13.89％。抗菌药物利用方面，限制使用级抗菌药物销售金额占比48.53％，非限制使用级抗菌药物DDDs占比75.31％。头孢菌素类抗菌药物的销售金额（12 771 265.34 元）和DDDs（291 542.31）均排名第1，其中以第二代头孢菌素为主（销售金额占比35.22％，DDDs占比42.98％）。销售金额排名前10位的药品均为注射剂，无特殊使用级品种，但包含有部分价格高、疗效一般的限制使用级抗菌药物。DDDs排名前10位的药品均为价格相对较低、疗效较好的非限制使用级和限制使用级抗菌药物，其中6种为口服剂型。结论：西安地区二级医院抗菌药物应用指标距国家要求还有一定距离；还应继续加强住院患者抗菌药物使用强度、门急诊患者抗菌药物使用率和Ⅰ类切口手术预防用药的管理，重点监控价格较高、疗效一般的抗菌药物品种的临床使用情况。 |
| ABSTRACT： | OBJECTIVE： To investigate the effectiveness of antibacterial clinical application special rectification activity， and to provide reference for rational use of antibacterials. METHODS： Referring to rational antibacterials application index stated in National Antibacterial Clinical Application Special Rectification Activity in 2013， the utilization of antibacterials in 36 secondary hospitals from Xi’an area during 2nd quarter in 2015 were analyzed retrospectively in terms of drug use index， types， consumption sum， DDDs and DDC， etc. RESULTS： Among 36 secondary hospitals from Xi’an area， there were only 3 hospitals up to the antibacterials use indicator standard （8.33％）； antibacterial use of 91.66％ inpatients was up to the standard； 55.56％of antibacterials use density was up to the standard； 50.00％ of outpatient antibacterials drug prescriptions was up to the standard； 77.78％ of emergency antibacterials drug prescriptions was up to the standard； 13.89％ of antibacterials was used in typeⅠincision surgery for prophylactic use. Restricted use antibacterial accounted for 48.53％ in consumption sum and Non-restricted use antibacterial accounted for 75.31％ in DDDs. The consumption sum （12 771 265.34 yuan） and DDDs （291 542.31） of cephalosporin ranked first， mainly were second generation cephalosporin （accounting for 35.22％ of consumption sum and 42.98％ of DDDs）. Top 10 drugs in the list of consumption sum were all injection； there was no special class of antibacterials but some antibacterias with high price and poor efficacy in top 10 ones. Top 10 drugs in the list of DDDs were non-restricted use and restricted use antibacterials with low price and good efficacy， among which there were 6 oral dosage forms. CONCLUSIONS： The application of antibacterials is still can not reach national standard in 36 secondary hospitals from Xi’an area. It is necessary to be further strengthen the management of inpatient antibacterial use density， the proportion of antibacterials used in outpatient and emergency patients， prophylactic application of antibacterials in type Ⅰ incision， the application of antibacterials with high price and poor therapeutic efficacy should be monitored closely. |
| 期刊： | 2016年第27卷第8期 |
| 作者： | 闵慧，李琼阁，王惠川，胡斌 |
| AUTHORS： | MIN Hui，LI Qiongge，WANG Huichuan，HU Bin |
| 关键字： | 抗菌药物；销售金额；用药频度；日均费用；使用分析 |
| KEYWORDS： | Antibacterials； Consumption sum； DDDs； DDC； Analysis of drug use |
| 阅读数： | 365 次 |
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