目的：为更好地提高护理人员对注射用奥美拉唑钠的风险识别能力，加强病区药品的风险管理，保障患者用药安全提供

参考。方法：选取某“三甲”医院该药使用频次相对较多的临床科室的护理人员作为研究对象，采用自行设计的问卷分别于2012、

2014 年对该院急诊科、消化科、ICU、CCU的护理人员进行注射用奥美拉唑钠用药风险相关知识的调查和分析。结果：2012 年和

2014 年分别发放问卷51 份和81 份，分别回收有效问卷51 份和81 份，有效回收率均为100％。两次调查中100％的受访护理人员

能够正确选择至少1 种溶剂，能正确选择2 种溶剂的分别占1.96％及3.70％；对该药滴注时间回答正确率分别为94.12％、96.30％；

对该药溶解后最好多长时间内用完的回答正确率均低于9％；对该药不良反应的回答正确率分别为3.92％、1.23％；对该药相互作

用的回答正确率分别为1.96％、6.17％；对该药与哪些制剂配伍相对稳定的回答正确率分别为17.65％、22.22％；临床遇到相关不

良反应的比例分别为25.49％、13.58％；临床遇到与其他注射剂配伍不当的比例分别为15.69％、22.22％，配伍不当次数最多的药

物为奥硝唑氯化钠注射液；希望加强医药护人员的继续教育的比例均在45％以上。结论：该院护理人员对注射用奥美拉唑钠的

用药风险认知存在一定不足，药品风险管理不够完善，风险防范意识相对薄弱。建议医院加强药品风险管理制度的建设，护理人

员加强药品风险知识的学习，并发挥临床药师在药品风险管理中的作用，以降低相关用药风险和减少药品不良事件的发生。

OBJECTIVE：To provide reference for better improving the risk perception of Omeprazole sodium for injection in

nurses in a third-grade class-A hospital，strengthening risk management of ward drugs and ensuring safety of patients. METHODS：

Nurses in the clinical departments in a third-grade class-A hospital where usage frequency of Omeprazole sodium for injection was

relatively more were adopted as study subjects and a self-designed questionnaire was used to investigate on related knowledge on

medication risk in nurses in emergency department，gastroenterology department，ICU and CCU in 2012 and 2014. RESULTS：51

and 81 questionnaires were distributed in 2012 and 2014，and 51 and 81 were effectively received with effective recovery of 100％

and 100％，respectively. In both surveys，100％ surveyed nurses could correctly choose one solvent at least，1.96％ and 3.70％

nurses could correctly choose 2 solvents；correct answering rates of intravenous administration time were 94.12％ and 96.30％，respectively；

correct answering rates of stable duration after preparation were both lower than 9％；correct answering rates of adverse

reaction of this drug were 3.92％ and 1.23％ ，respectively；correct answering rates of interaction of this drug were 1.96％ and

6.17％，respectively；correct answering rates of stable formulation of this drug were 17.65％ and 22.22％，respectively；the proportion

of nurses observing ADRs were 25.49％ and 13.58％，respectively；the proportion of nurses finding inappropriate compatibility

were 15.69％ and 22.22％，respectively，Ornidazole and sodium chloride injection was the most used incompatible drug；45％ or

more nurses hoping to strengthen the continuing education of nursing personnel. CONCLUSIONS：Nurses in this third-grade

class-A hospital lack certain knowledge on the medication risk of Omeprazole sodium for injection，the drug risk management is

not sufficient，and awareness prevention of drug risk is relative weak. It is suggested that the hospital should strengthen drug risk

management system，nurses should strengthen the learning about drug risk and play the role of clinical pharmacists in the drug risk

management to reduce the related drug risk and incidence of adverse reactions.