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脆性骨折术后规范化抗骨质疏松症药物治疗管理模式建立
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| 篇名： | 脆性骨折术后规范化抗骨质疏松症药物治疗管理模式建立 |
| TITLE： | Establishment of a standardized management model for postoperative anti-osteoporosis medication in patients with brittle fractures |
| 摘要： | 目的 探讨驻科药师构建与推广脆性骨折术后规范化抗骨质疏松症药物治疗管理新模式，为驻科药师开展临床药学服务提供参考。方法驻科药师分析统计2023年7月至2024年3月595例患者脆性骨折术后数据，采用PDCA（计划-执行-检查-行动）循环法，在临床实践中发现问题并展开调研，通过在患者治疗前、治疗中和治疗后嵌入临床药师干预服务，制定药物治疗路径，形成脆性骨折术后规范化抗骨质疏松症药物治疗管理模式；同时依托国家骨科与运动康复临床医学研究中心的国家脆性骨折大数据平台，构建脆性骨折术后规范化抗骨质疏松症药物治疗管理数据模块，为驻科药师药学服务模式效果评价提供大数据支持。结果通过PDCA循环法的持续改进，骨科脆性骨折术后骨质疏松症诊断比例从驻科前的9%上升至81%，药物治疗比例由4%增加到75%，骨密度和骨代谢的检查比例也显著提升，对患者长期预后的改善产生了积极作用。结论驻科药师建立的脆性骨折术后规范化抗骨质疏松症药物治疗管理模式，提高了临床医师对骨质疏松症的诊疗水平，保障了骨质疏松症患者的合理用药，具有较好的推广和应用价值。 |
| ABSTRACT： | OBJECTIVE To investigate the establishment and promotion of a new standardized management model for anti- osteoporosis medication after fragility fracture surgery by resident clinical pharmacists， and provide references for resident pharmacists to carry out clinical pharmaceutical services. METHODS From July 2023 to March 2024，595 post-brittle fracture surgery patients were enrolled. Using the PDCA （plan-do-check-act） cycle，resident clinical pharmacists identified issues and conducted investigations in clinical practice. Through integrating clinical pharmacist intervention services before， during and after treatment， a medication treatment pathway was developed， thereby establishing a standardized management model for anti- osteoporosis treatment following fragility fracture surgery. Leveraging the National Brittle Fracture Big Data Platform （under the National Clinical Research Center for Orthopedics and Sports Rehabilitation）， a dedicated data module was constructed， providing big data support to evaluate the efficacy of this pharmaceutical care model. RESULTS Continuous PDCA cycle driven improvements significantly increased the proportion of osteoporosis diagnosis （from 9% before intervention to 81%） and proportion of drug treatment （from 4% to 75%）.The proportions of bone density and bone metabolism testing also rose markedly，positively impacting long-term patient outcomes. CONCLUSIONS The establishment of a standardized management model for anti- osteoporosis treatment following fragility fracture surgery by resident clinical pharmacists has enhanced clinicians’ diagnostic and therapeutic capabilities for osteoporosis， ensures rational medication use in osteoporosis patients， and demonstrates significant potential for widespread adoption and application. |
| 期刊： | 2025年第36卷第15期 |
| 作者： | 刘浩；杨滢霖；蔡乐；李树；朱曼；陈孟莉 |
| AUTHORS： | LIU Hao，YANG Yinglin，CAI Le，LI Shu，ZHU Man，CHEN Mengli |
| 关键字： | 脆性骨折；驻科药师；骨质疏松症；药学服务；临床药学；PDCA |
| KEYWORDS： | fragility fracture； resident pharmacists； osteoporosis； pharmaceutical service； clinical pharmacy； PDCA |
| 阅读数： | 16 次 |
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