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集采政策对某三级甲等肿瘤专科医院非小细胞肺癌治疗药品使用的影响
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| 篇名： | 集采政策对某三级甲等肿瘤专科医院非小细胞肺癌治疗药品使用的影响 |
| TITLE： | Effects of centralized volume-based procurement policy on the use of drugs for non-small cell lung cancer in a third-grade class-A cancer hospital |
| 摘要： | 目的 分析国家集中带量采购（以下简称“集采”）政策对医疗机构抗肿瘤药使用的影响。方法采用间断时间序列模型分析山西省某三级甲等肿瘤专科医院2018年1月－2021年12月多西他赛、吉西他滨、培美曲塞二钠的月度采购量和采购金额的变化情况。结果与结论集采政策执行后，中选药品和非中选药品均有不同程度降价，且中选药品的降价幅度远大于非中选药品。政策实施当月，该院多西他赛的平均月度采购量和采购金额均显著下降，而吉西他滨和培美曲塞二钠的月度采购量和采购金额均显著上升（P＜0.05或P＜0.01）。政策实施后，吉西他滨的平均月度采购量和采购金额均呈下降趋势，而多西他赛和培美曲塞二钠的平均月度采购量和采购金额均呈上升趋势（P＜0.05或P＜0.01）。建议医疗机构加强药事管理，避免对非中选药品“一刀切”；相关部门可考虑进一步扩大抗肿瘤药的集采范围或开展抗肿瘤药专项集采，以节约医保资金，减少医疗支出。 |
| ABSTRACT： | OBJECTIVE To analyze the effects of centralized volume-based procurement policy （hereinafter referred to as “centralized procurement”） on the use of anti-tumor drugs in medical institutions. METHODS The interrupted time series model was used to analyze the changes in the monthly purchase volume and purchase amount of docetaxel， gemcitabine and pemetrexed disodium in a third-grade class-A cancer hospital in Shanxi province from January 2018 to December 2021. RESULTS & CONCLUSIONS After the implementation of the centralized procurement policy， both the selected drugs and the non-selected drugs had different degrees of price reduction， and the price reduction of the selected drugs was far greater than that of the non- selected drugs； average monthly purchase volume and amount of docetaxel decreased significantly in that month after the implementation of the policy， while those of gemcitabine and pemetrexed disodium increased significantly （P＜0.05 or P＜0.01）. After the implementation of the policy， the average monthly purchase volume and amount of gemcitabine showed a downward trend， while those of docetaxel and pemetrexed disodium showed an upward trend （P＜0.05 or P＜0.01）. It is suggested that hospitals should strengthen pharmaceutical administration， and avoid adopting a “one size fits all” approach to non-selected drugs； relevant departments should further expand the collection range of anti-tumor drugs or carry out special collection of anti-tumor drugs， so as to save medical insurance funds and reduce medical expenses. |
| 期刊： | 2023年第34卷第16期 |
| 作者： | 崔凯霞；李卓然；赵耀伟；郝志英 |
| AUTHORS： | CUI Kaixia，LI Zhuoran，ZHAO Yaowei，HAO Zhiying |
| 关键字： | 国家集中带量采购；间断时间序列；多西他赛；吉西他滨；培美曲塞二钠 |
| KEYWORDS： | centralized volume-based procurement； interrupted time series； docetaxel； gemcitabine； pemetrexed disodium |
| 阅读数： | 88 次 |
| 本月下载数： | 10 次 |
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