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贵州省老年结核病患者多重用药负担及影响因素分析
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| 篇名： | 贵州省老年结核病患者多重用药负担及影响因素分析 |
| TITLE： | Analysis of the burden of polypharmacy and its influencing factors among elderly tuberculosis patients in Guizhou province |
| 摘要： | 目的 了解贵州省老年结核病患者多重用药负担及其影响因素，为减轻患者用药负担提供参考依据。方法2022年4－7月，采用便利抽样法在贵州省贵阳市、毕节市、黔东南苗族侗族自治州三地的3所结核病定点医院抽取405例老年结核病门诊患者作为调查对象，采用一般情况调查表、用药生活问卷（LMQ）进行面对面调查。运用描述性分析、单因素方差分析、多元线性回归分析了解老年结核病患者的多重用药负担得分情况并探讨影响老年结核病患者多重用药负担的因素。结果405例老年结核病患者的多重用药负担总得分为（112.65±14.59）分，高于LMQ高负担标准的阈值（110分）。多元线性回归分析结果显示，年龄80～92岁、自费+医保、复治、耐药、有药物不良反应是老年结核病患者多重用药负担的危险因素（P＜0.05）；居住地为城镇和服药管理方式为家庭成员管理、志愿者管理、智能工具辅助管理是其保护因素（P＜0.05）。结论贵州省老年结核病患者的多重用药负担较重，且受患者年龄、居住地、药费支付方式、治疗分类、是否耐药、药物不良反应、服药管理方式的影响。医护人员应根据多重用药负担的影响因素为重点人群提供用药指导和帮助，以减轻其多重用药负担。 |
| ABSTRACT： | OBJECTIVE To understand the polypharmacy burden and influencing factors of elderly tuberculosis （TB） in Guizhou province， and to provide reference for reducing the polypharmacy burden of patients. METHODS From April to July 2022， 405 elderly TB outpatients were selected from three designated TB hospitals in Guiyang City， Bijie City， and Qiandongnan Miao and Dong Autonomous Prefecture of Guizhou Province by convenience sampling method as investigation objects. The general situation questionnaire and the Living with Medicines Questionnaire （LMQ） were used for face-to-face survey. Descriptive analysis， one-way ANOVA and multivariate linear regression analysis were used to understand the score of polypharmacy burden of elderly TB patients and explore the factors effecting polypharmacy burden in TB patients. RESULTS The total polypharmacy burden score of 405 elderly TB patients was （112.65±14.59） points， which was higher than the threshold （110 points） for high burden standard in LMQ. Multivariate linear regression analysis showed that aged 80 to 92 years， self-financed+medical insurance， retreatment， drug resistance， and adverse drug reactions were the risk factors for polypharmacy burden in elderly TB patients （P＜0.05）； living in the city， family member management， volunteer management and intelligent tool-assisted management were the protective factors （P＜0.05）. CONCLUSIONS The burden of polypharmacy in elderly TB patients from Guizhou province is heavy， and is influenced by patient’s age， residence， payment method， treatment classification， drug resistance， adverse drug reactions， and medication management. It is recommended that medical staff should provide key populations with medication guidance based on influential factor for polypharmacy burden so as to reduce their polypharmacy burden. |
| 期刊： | 2023年第34卷第09期 |
| 作者： | 胡元霞；王芸；方世林；禄晓龙 |
| AUTHORS： | HU Yuanxia，WANG Yun，FANG Shilin，LU Xiaolong |
| 关键字： | 结核病；多重用药负担；老年人；影响因素 |
| KEYWORDS： | tuberculosis； polypharmacy burden； elderly； |
| 阅读数： | 135 次 |
| 本月下载数： | 5 次 |
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