牡丹皮采收加工方法和质量控制研究进展
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篇名: 牡丹皮采收加工方法和质量控制研究进展
TITLE: Research progress on harvesting and processing methods and quality control of Moutan Cortex
摘要: 牡丹皮为常用大宗药材,在我国有两千多年的药用历史。本研究系统总结了牡丹皮的采收期与生长年限,产地加工过程中涉及的刮皮、抽心、趁鲜切制、硫磺熏蒸、干燥和贮存,以及商品规格等级、质量控制方法等方面的研究概况。结果显示,牡丹皮一般种植5~6年后在秋季的晴天采收为宜;连丹皮的整体质量优于刮丹皮,故建议牡丹皮加工过程中可不刮皮而只抽心;牡丹皮趁鲜切制较为适宜,可避免饮片中有效成分在中间流通环节因贮存时间久而造成损失;牡丹皮趁鲜切制后宜采用远红外、避光、真空包装等适当的方法干燥、贮藏,可最大程度地保存药效;硫磺熏蒸不仅影响牡丹皮的质量,且极易导致二氧化硫超标,故在产地加工过程中不建议对牡丹皮进行硫熏处理;牡丹皮可分为凤丹皮、连丹皮、刮丹皮3种规格,根据其长度和直径可划分为4个等级。目前已有多种方法(高效液相色谱法、气相色谱-质谱法等)用于牡丹皮质量控制研究,但是否能反映牡丹皮的整体质量还需更深入的研究和探讨。牡丹皮是否刮皮应结合其他相关因素(如临床药效、农药残留及重金属含量等)综合考虑,其趁鲜切制的工艺参数仍需进一步优化。
ABSTRACT: Moutan Cortex, a common bulk traditional Chinese medicine, has a long medicinal history of more than 2 000 years. This study systematically summarizes the research overview of Moutan Cortex in the term of harvest time and growth years, and peeling, heart pumping, cutting while fresh, sulfur fumigation, drying and storage involved in the processing in producing area, as well as commodity specifications and grades, quality control methods. The results show that it is suitable to harvest Moutan Cortex on sunny days in autumn after 5-6 years of planting. The overall quality of Moutan Cortex retained cork is better than that of Moutan Cortex removed cork. It is recommended that the processing of Moutan Cortex may be considered to retain cork but remove xylem. It is more suitable to cut Moutan Cortex when it is fresh, in order to avoid the loss of the active ingredients due to the long storage time in the middle circulation. The fresh-cut pieces of Moutan Cortex can be dried and stored by the appropriate methods such as far-infrared drying, avoiding light and vacuum packing, which can preserve the efficacy to the greatest extent. Sulfur fumigation treatment not only affects the quality of Moutan Cortex, but also easily leads to excessive sulfur dioxide. It is not recommended to use the method of sulfur fumigation in the processing of Moutan Cortex in the production area. Moutan Cortex can be divided into three specifications: Fengdan, Liandan and Guadan, which are divided into four grades according to their length and diameter. At present, many methods (HPLC, GC-MS) have been used for quality control of Moutan Cortex, but whether they can reflect the overall quality of Moutan Cortex needs further research and discussion. Whether the Moutan Cortex is scraped should be considered in combination with other relevant factors (such as clinical efficacy, pesticide residues and heavy metal content), and the process parameters of fresh-cut Moutan Cortex still need to be further optimized.
期刊: 2022年第33卷第23期
作者: 刘洋,郭庆梅,宋艳梅
AUTHORS: LIU Yang,GUO Qingmei,SONG Yanmei
关键字: 牡丹皮;采收;加工;质量控制
KEYWORDS: Moutan Cortex; harvesting; processing; quality control
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