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稳定性冠心病患者实施药物治疗管理服务的经济学评价
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| 篇名： | 稳定性冠心病患者实施药物治疗管理服务的经济学评价 |
| TITLE： | Economic evaluation of medication therapeutical management services for patients with stable coronary heart disease |
| 摘要： | 目的 探讨对稳定性冠心病患者实施药物治疗管理（MTM）服务的经济学价值。方法将140例稳定性冠心病患者随机分为对照组和干预组，各70例。对照组患者接受常规医疗服务，干预组患者在此基础上接受规范的MTM服务。比较两组患者的用药依从性评分、满意度、安全性指标和疗效指标。从全社会角度出发，采用最小成本分析法，就药师对稳定性冠心病患者的MTM服务进行经济学评价。结果共有15例患者未完成本次研究，其中干预组5例、对照组10例；随访周期内未有患者发生死亡终点事件。干预组患者的用药依从性量表（MMAS-8）评分、药物沟通维度的满意度评分和总体满意度评分均显著高于对照组（P＜0.01）；两组患者的血压达标率、血脂达标率、药品不良反应发生率和急性冠状动脉综合征发生率比较，差异均无统计学意义（P＞0.05）。干预组患者的治疗总成本显著低于对照组（P＜0.01），敏感性分析结果与最小成本分析结果一致。结论药师对稳定性冠心病患者实施MTM服务，可降低患者治疗总成本、节约医疗资源，具有经济性。 |
| ABSTRACT： | OBJECTIVE To ex plore the economic value of medication therapeutical management （MTM）service for patients with stable coronary disease. METHODS Totally 140 patients with stable coronary disease were divided into a control group and a intervention group ，70 cases in each group. Patients in control group were received routine medical services ，and patients in intervention group additionally received standardized MTM services on this basis. Medication complication ，satisfaction degree ， safety indexes and efficacy indexes were compared between 2 groups. From the perspective of the whole society ，the economic value of MTM service for patients with stable coronary disease were evaluated by pharmacists using cost minimization analysis. RESULTS A total of 15 patients did not complete the study ，including 5 cases in intervention group and 10 cases in control group ； there was no death endpoint during the follow-up period. MMAS- 8 score，satisfaction score of drug communication dimension and score of overall satisfactionin of intervention group were obviously higher than control group （P＜0.01）. There was no significant difference in blood pressure standard rate ，blood lipid standard rate ，the incidence of adverse drug reaction ，and the incidence of acute coronary events between 2 groups（P＞0.05）. The total cost of intervention group was lower than that of control group （P＜ 0.01）；the results of sensitivity analysis were consistent with those of cost minimization analysis. CONCLUSIONS Pharmacists implement MTM service for patients with stable coronary disease can reduce total cost ，save medical resources and has economic advantages. |
| 期刊： | 2022年第33卷第08期 |
| 作者： | 蒋欢欢，王紫监，王志秀，谷秀林，李世滋 |
| AUTHORS： | JIANG Huanhuan ，WANG Zijian，WANG Zhixiu ，GU Xiulin，LI Shizi |
| 关键字： | 药物治疗管理；稳定性冠心病；经济学评价；药学服务 |
| KEYWORDS： | medication thera peutical management ；stable coronary disease ；economic evaluation ；pharmaceutical care |
| 阅读数： | 140 次 |
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