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改良复方聚乙二醇电解质散肠道准备方法在便秘患者肠镜检查中的应用
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| 篇名： | 改良复方聚乙二醇电解质散肠道准备方法在便秘患者肠镜检查中的应用 |
| TITLE： | Application of Modified Preparation Method of Compound Polyethylene Glycol Electrolyte Powder in Colonoscopy for Patients with Constipation |
| 摘要： | 目的：探讨改良复方聚乙二醇电解质散（SF-PEG）肠道准备方法在便秘患者肠镜检查中的应用效果及安全性。方法：将2020年1－8月在川北医学院附属医院肛肠科拟行肠镜检查的便秘患者共160例按照随机数字表法分为观察组和对照组，各80例。对照组患者在检查当日凌晨3：00口服SF-PEG2盒（兑入温水3000mL中），2h内服完。观察组患者在检查前一晚20：00和检查当日清晨5：00分别口服SF-PEG1盒（兑入温水1500mL中），1h内喝完；并于检查当日清晨7：00口服二甲硅油散1瓶（兑入温水75mL中）。比较两组患者的肠道准备满意度、肠道气泡评分、肠镜检查操作时间、息肉检出情况、患者耐受率和再次肠道准备接受率及不良反应发生情况。结果：两组患者均顺利完成肠道准备及肠镜检查。观察组患者的肠道准备总满意率、肠道气泡满意率、息肉检出率、患者耐受率和再次肠道准备接受率均显著高于对照组（P＜0.05），恶心呕吐的发生率和不良反应总发生率显著低于对照组（P＜0.05），肠镜检查操作时间显著短于对照组（P＜0.05）。结论：应用分次口服SF-PEG联合二甲硅油散的方法对便秘患者做肠镜检查前的肠道准备，具有肠道准备满意度高、肠道气泡少、检查操作时间短、息肉检出率高、患者耐受率和再次肠道准备接受率高、不良反应少等优点，是一种安全有效的肠道准备方法。 |
| ABSTRACT： | OBJECTIVE：To inves tigate the application effect and safety of modified compound polyethylene glycol electrolyte powder（SF-PEG）in intestinal preparation method for patients with constipation undergoing colonoscopy. METHODS ：From Jan. 2020 to Aug. 2020，160 patients with constipation undergoing colonoscopy in anorectal department of the affiliated hospital of North Sichuan Medical College were randomly divided into observation group and control group ，with 80 cases in each group. The patients in the control group took 2 boxes of SF-PEG （mixed into 3 000 mL warm water ）orally at 3：00 a.m. on the day of examination，and finished within 2 hours. The patients in the observation group took 1 box of SF-PEG （mixed into 1 500 mL warm water）at 20：00 the night before the examination and 5：00 in the morning of the day of examination ，and drank it within 1 hour；1 bottle of Dimethylsiloxane powder （mixed into 75 mL warm water ）was taken orally at 7：00 a.m. on the inspection day. The satisfaction of intestinal preparation ，intestinal bubble score ，operation time of colonoscopy ，detection of polyps ，tolerance rate ， acceptance rate of repeating intestinal preparation of patients and incidence of adverse reactions were compared between the two groups. RESULTS ：The patients of 2 groups successfully completed bowel preparation and colonoscopy. The intestinal preparation total satisfaction rate ，intestinal bubble satisfaction rate ，polyp detection rate ，tolerance rate and repeating intestinal preparation acceptance rate of patients of observation group were significantly higher than control group （P＜0.05），while the incidence of nausea and vomiting and total incidence of adverse reactions were significantly lower than control group （P＜0.05），and the operation time of colonoscopy was significantly shorter than control group （P＜0.05）. CONCLUSIONS ：Oral administration of SF-PEG in batches combined with Dimethylsiloxane powder for bowel preparation in patients with constipation before colonoscopy have the advantages of high satisfaction with bowel preparation ，less intestinal bubbles ，short operation time ，high detection rate of polyps，high tolerance rate of patients ，high acceptance rate of repeating intestinal preparation and less adverse reactions. It is a safe and effect method for intestinal preparation. |
| 期刊： | 2021年第32卷第13期 |
| 作者： | 赵兵，吴至久，唐学贵，孔鹏飞，陈泰宇，刘仕鸿 |
| AUTHORS： | ZHAO Bing，WU Zhijiu，TANG Xuegui ，KONG Pengfei ，CHEN Taiyu，LIU Shihong |
| 关键字： | 复方聚乙二醇电解质散；二甲硅油散；便秘；肠镜检查；肠道准备 |
| KEYWORDS： | Compound polyethylene glycol electrolyte powder；Dimethylsiloxane powder ；Constipation；Colonoscopy；Intestinal |
| 阅读数： | 420 次 |
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