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茵栀黄口服液辅助治疗新生儿母乳性黄疸的临床观察
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| 篇名： | 茵栀黄口服液辅助治疗新生儿母乳性黄疸的临床观察 |
| TITLE： | |
| 摘要： | 目的：观察茵栀黄口服液辅助治疗新生儿母乳性黄疸的疗效和安全性。方法： 112例母乳性黄疸新生儿随机均分为对照组和观察组。对照组患儿均停止母乳喂养3 d，采用人工喂养，给予保暖、营养支持、维持水电解质及酸碱平衡、蓝光照射等常规治疗，严重者给予保肝、酶诱导剂等药物治疗；观察组患儿在对照组治疗的基础上给予茵栀黄口服液10 ml，每日2次。两组患儿疗程均为 7 d。观察两组患儿的临床疗效，治疗前后血清总胆红素（TBIL）水平及不良反应发生情况。结果：观察组患儿总有效率显著高于对照组，差异有统计学意义（P＜0.05）；治疗后，两组患儿TBIL水平均显著低于同组治疗前，均随时间逐渐降低，且观察组低于对照组，差异均有统计学意义（P＜0.05）。两组患儿不良反应发生率比较，差异无统计学意义（P＞0.05）。结论：在常规治疗的基础上，茵栀黄口服液辅助治疗母乳性新生儿黄疸的疗效较好，且安全性较好。 |
| ABSTRACT： | OBJECTIVE：To observe the clinical efficacy and safety of Yinzhihuang oral liquid in the adjuvant treatment of neonatal breast-feeding faundice. METHODS： 112 newborns with faundice were randomly divided into control group and observation group. Control group stopped breast-feeding for 3 d and given artificial feeding， as well as keeping warm， nutritional support， maintaining water and electrolyte and acid-base balance， blue light irradiation and severe patients were given liver protection， enzyme inducers； observation group was additionally given Yinzhihuang oral liquid 10 ml， twice a day. The treatment course was 7 d. Clinical efficacy， and serum total bilirubin （TBIL） level before and after treatment， and incidence of adverse reactions in 2 groups were observed. RESULTS： The total effective rate in observation group was significantly higher than control group， the difference was statistically significant（P＜0.05）. After treatment， TBIL level in 2 groups was significantly lower than before and gradually decreased with time， and observation group was lower than control group， the differences were statistically significant（P＜0.05）. The incidence of adverse reactions of 2 groups was no statistically significant（P＞0.05）. CONCLUSIONS： Based on the conventional treatment， Yinzhihuang oral liquid can be used in the adjuvant treatment of neonatal breast-feeding faundice， with good efficacy and good safety. |
| 期刊： | 2015年第26卷第36期 |
| 作者： | 唐帷微，吕宗杰，王梓，谢茜 |
| AUTHORS： | TANG Wei-wei，LYU Zong-jie，WANG Zi，XIE Qia |
| 关键字： | 茵栀黄口服液；新生儿；母乳性黄疸；疗效；安全性 |
| KEYWORDS： | Yinzhihuang oral liquid； Newborn； Breast-feeding faundice； Efficacy； Safety |
| 阅读数： | 247 次 |
| 本月下载数： | 0 次 |
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