目的：探讨临床药师在化脓性脑膜炎患者抗感染治疗中的作用与切入点。方法：临床药师对1 例化脓性脑膜炎患者进行

药学监护，协助医师调整抗菌药物治疗方案，先后使用万古霉素+头孢曲松钠、美罗培南+万古霉素、左氧氟沙星+万古霉素抗感

染，并处理美罗培南和左氧氟沙星的药品不良反应。结果：医师采纳临床药师建议，患者的感染得到控制，药品不良反应症状消

失，予以出院。结论：临床药师对化脓性脑膜炎患者进行药学监护，协助医师制订安全、有效的抗感染方案，及时解决药品不良反

应，促进临床合理用药。

OBJECTIVE：To explore the role and breakthrough point of clinical pharmacist in the anti-infective therapy for a

patient with purulent meningitis. METHODS：Clinical pharmacists provided pharmaceutical care for a patient with purulent meningitis，

assisted physicians to adjust therapy plan of antibiotics，i.e. anti-infective therapy of vancomycin+ceftriaxone sodium，meropenem+

vancomycin，levofloxacin+vancomycin successively；disposed ADR induced by meropenem and levofloxacin. RESULTS：The

physicians adopted the suggestions of clinical pharmacists，the infection symptom had been controlled，and ADR disappeared；and

then the patient was discharged from hospital. CONCLUSIONS：Clinical pharmacists provide pharmaceutical care for patient with

purulent meningitis，assist the physicians to develop safe and effective anti-infective therapy plan，and dispose ADR timely so as to

promote rational drug use in the clinic.