目的：观察生化汤辅助治疗早期妊娠流产的疗效及安全性。方法：228 例早期妊娠流产患者按随机数字表法分为对照组

和观察组，各114 例。对照组患者服用米非司酮25 mg，bid，并于第4 天加服米索前列醇600 μg，qd，共治疗4 d；观察组患者在对照

组基础上于第4 天口服米索前列醇后2 h 加服生化汤1 次，然后bid，连续服用7 d。观察两组患者流产率、出血时间、出血量、流产

后正常活动时间及不良反应发生率。结果：观察组患者流产率为96.5％，高于对照组的85.1％，组间比较差异有统计学意义（P＜

0.05）；观察组患者的出血量、出血时间、正常活动时间均显著低于或短于对照组，组间比较差异有统计学意义（P＜0.05）；观察组患

者不良反应发生率显著低于对照组，组间比较差异有统计学意义（P＜0.05）。结论：生化汤辅助治疗早期妊娠流产疗效较好，且不

良反应发生率低。

OBJECTIVE：To observe therapeutic efficacy of adjunctive treatment of Shenghua decoction for abortion in the early

pregnancy. METHODS：228 patients with abortion in the early pregnancy collected from our hospital were randomly divided into

control group and observation group with 114 cases in each group. Control group was given mifepristone 25 mg，bid，and additional

misoprostol 600 μg on the forth day，qd，for 4 days. Observation group was additionally given misoprostol orally on the forth

day，2 h later，Shenghua decoction，bid，for consecutive 7 days. The rate of abortion，bleeding time，amount of bleeding，normal

activity time after abortion，and the incidence of ADR were observed in 2 groups. RESULTS：The rate of abortion in observation

group was 96.5％，which was higher than that of control group（85.1％），with statistical significance（P＜0.05）. The bleeding

time，amount of bleeding and normal activity time of observation group were significantly lower or shorter then those of control

group，with statistical significance （P＜0.05）. The incidence of ADR in observation group was significantly lower than control

group，with statistical significance（P＜0.05）. CONCLUSIONS：The adjunctive treatment of Shenghua decoction have good effect

on abortion in the early pregnancy with less ADR.