目的：探讨大株红景天注射液在骨折患者围手术期中对患肢肿胀及疼痛程度的作用。方法：120 例闭合性新鲜四肢长骨

骨折患者按照随机数字表法分成试验组和对照组，各60 例。两组患者均采用切开复位钢板内固定术进行治疗。手术前后对照组

患者使用常规药物进行对症及抗炎治疗；试验组患者在对照组基础上，加用大株红景天注射液10 ml（加入250 ml 5％葡萄糖注射

液中）静脉滴注，qd。两组均10 d 为1 个疗程。观察并比较两组患者术前、术后1 d、术后3 d 的患肢肿胀程度，手术当天及术后1、

2、3、7 d 的疼痛程度，并发症发生情况和平均住院天数。结果：试验组患者的患肢肿胀程度、术后疼痛程度、并发症发生率、平均住

院天数均低于或短于对照组，差异有统计学意义（P＜0.05 或P＜0.01）。结论：在骨折围手术期中应用大株红景天注射液可活血化

瘀、消肿止痛，减轻患者肢体肿胀及疼痛程度，降低并发症发生率，缩短住院天数。

OBJECTIVE：To observe therapeutic efficacy of Rhodiola wallichiana injection for swelling and pain in fracture patients

during perioperative period. METHODS：120 patients with closed fresh extremity long bones fracture were randomly divided into

trial group and control group，with 60 cases in each group. Both groups received open reduction and plate fixation. Before and after operation，

control group was given routine medicine and anti-inflammatory treatment；trial group was additionally given R. wallichiana injection

10 ml（250 ml added into 5％ Glucose injection）intravenously，qd，on the basis of control group. A treatment course lasted for

10 d. The swelling degree before operation，1 d and 3 d after operation，pain degree on the day of operation and 1，2，3 and 7 d after

operation，complication and average length of stay were observed and compared between 2 groups. RESULTS：The extent of swelling

and pain，the incidence of complications and average hospitalization days of trial group were lower or shorter than control group，with

statistical significance（P＜0.05）. CONCLUSIONS：R. wallichiana injection can promote blood circulation and remove blood stasis，

ease the hydropsia and pain，relieve swelling and pain，reduce the incidence of complications and shorten hospitalization day.