目的：评价我院开展抗菌药物临床应用专项整治的效果。方法：分别于2010 年5 月－2011 年4 月、2011 年5 月－2012 年

4 月、2012 年5 月－2013 年4 月、2013 年5 月－2014 年4 月4 个时间段，从我院所有Ⅰ类切口手术的出院病历中随机抽取100 份，

共计400 份，对抗菌药物使用强度、Ⅰ类切口手术围术期抗菌药物使用率、药物利用指数、围术期抗菌药物选用的种类、给药时间

等评价指标进行统计分析。结果：自2011 年5 月开展抗菌药物临床应用专项整治活动后，我院Ⅰ类切口手术围术期抗菌药物使

用率从96％下降至33％，药物利用指数从1.44 下降至0.79，药物选择合理率从19.8％上升至100％，给药时间合理率从43.8％上

升至100％。结论：抗菌药物临床应用专项整治活动的开展，使我院Ⅰ类切口手术围术期抗菌药物的合理用药评价指标均明显

改善。

OBJECTIVE：To evaluate the effect of clinical antibiotics use special rectification in our hospital. METHODS：100

discharged medical records of type Ⅰ incision surgery were randomly sampled from our hospital during May in 2010 to Apr. in

2011，May in 2011 to Apr. in 2012，May in 2012 to Apr. in 2013，May in 2013 to Apr. in 2014，totaling 400 records. And then

evaluation indicators were analyzed statistically，such as antibiotics use intensity，perioperative DDDs of antibiotics in typeⅠincision

surgery，DUI，types of antibiotics during perioperative period，medication time，etc. RESULTS：Since the implementation of

clinical antibiotics use special rectification in May 2011，the utilization ratio of antibiotics in typeⅠincision surgery of our hospital

decreased from 96％ to 33％；DUI decreased from 1.44 to 0.79；while reasonable rate of drug selection increased from 19.8％ to

100％，and that of medication time increased from 43.8％ to 100％. CONCLUSIONS：Rational medication evaluation indicators in

typeⅠincision surgery of our hospital have been improved after the implementation of clinical antibiotics use special rectification.