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妊娠期是否规律补铁对母婴血红蛋白水平和围产期并发症的影响
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| 篇名： | 妊娠期是否规律补铁对母婴血红蛋白水平和围产期并发症的影响 |
| TITLE： | |
| 摘要： | 目的：研究妊娠期是否规律补铁对孕产妇和新生儿血红蛋白水平和围产期并发症的影响。方法：回顾性收集2016年5月－2017年5月在我院分娩的606例孕产妇的资料，根据妊娠期是否规律补铁分为规律补充铁剂组（142例）、不规律补充铁剂组（218例）和未补充铁剂组（246例）。3组孕产妇均于产前及产后3～7 d检测血红蛋白水平；记录3组孕产妇妊娠期高血压、胎膜早破和产褥感染的发生率；记录3组孕产妇分娩的新生儿出生体质量，并检测新生儿脐血血红蛋白水平，同时，采用Apgar评分评估新生儿出生后有无缺氧窒息情况；统计3组孕产妇的平均住院天数。结果：规律补充铁剂组产前及产后的血红蛋白水平显著高于不规律补充铁剂组及未补充铁剂组，妊娠期高血压、胎膜早破及产褥感染的发生率显著低于不规律补充铁剂组及未补充铁剂组，平均住院天数均显著少于不规律补充铁剂组及未补充铁剂组，其分娩的新生儿脐血血红蛋白水平和出生体质量均显著高于不规律补充铁剂组及未补充铁剂组，差异均有统计学意义（P＜0.05）；但3组孕产妇便秘发生率和其分娩的新生儿Apgar评分＜7分者的比例比较，差异均无统计学意义（P＞0.05）。结论：妊娠期规律补铁能显著降低孕产妇缺铁性贫血、妊娠期高血压、胎膜早破、产褥感染的发生率，减少住院天数，增加新生儿出生体质量，提高新生儿脐血血红蛋白水平，且安全性较好。 |
| ABSTRACT： | OBJECTIVE： To study the effects of regular iron supplementation on hemoglobin and perinatal complication of pregnant women and neonates. METHODS： In retrospective analysis， the information of 606 pregnancy women were collected from Chongqing People’s Hospital during May 2016-May 2017. According to the regularity of iron supplementation， they were divided into regular iron supplementation group （142 cases）， irregular iron supplementation group （218 cases） and no iron supplementation group （246 cases）. The levels of hemoglobin in pregnant women were determined in 3 groups before childbirth and 3-7 d after childbirth. The incidence of gestational hypertension， premature rupture of membranes and puerperal infection in pregnant women were recorded in 3 groups. Birth weights of neonates delivered by pregnant women were recorded in 3 groups， and the levels of hemoglobin in umbilical cord blood of neonates were also detected. Apgar score was used to evaluate whether neonates were born with hypoxia or asphyxia. The average days of hospitalization were counted for pregnant women of 3 groups. RESULTS： The levels of hemoglobin in regular ion supplementation group before and after childbirth were significantly higher than irregular ion supplementation group and no ion supplementation group； the incidence of gestational hypertension， premature rupture of membranes and puerperal infection were significantly lower than irregular ion supplementation group and no ion supplementation group， average hospitalization days were significantly less than irregular ion supplementation group and no ion supplementation group， the levels of hemoglobin in umbilical cord blood of neonates and birth weight in regular ion supplementation group were significantly higher than irregular ion supplementation group and no ion supplementation group， with statistical significance （P＜0.05）. There was no statistical significance in the incidence of constipation in pregnant women and the ratio of Apgar score of the neonates ＜7 among 3 groups （P＞0.05）. CONCLUSIONS： Regular iron supplementation can remarkably decrease the incidence of anemia， gestational hypertension， premature rupture of membrane and puerperal infection in pregnant women， shorten average hospitalization time， and increase average birth weight of neonates and the level of hemoglobin in umbilical cord blood. |
| 期刊： | 2018年第29卷第12期 |
| 作者： | 谭晓青，罗业涛，黄怡 |
| AUTHORS： | TAN Xiaoqing，LUO Yetao，HUANG Yi |
| 关键字： | 铁剂；妊娠期贫血；血红蛋白；并发症 |
| KEYWORDS： | Iron agent；Anemia in pregnancy；Hemoglobin； Complication |
| 阅读数： | 416 次 |
| 本月下载数： | 5 次 |
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