重庆市34家医院2013-2015年生物制品及生化药品的利用分析
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篇名: 重庆市34家医院2013-2015年生物制品及生化药品的利用分析
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摘要: 目的:了解生物制品及生化药品在重庆市医院的使用现状及变化趋势,为进一步促进该类药物的临床合理使用提供参考。方法:采用金额排序分析和用药频度(DDDs)分析等方法,收集重庆市34家医院2013-2015年生物制品及生化药品的使用数据,并进行汇总、统计和分析。结果:重庆市34家医院3年间生物制品及生化药品的使用金额从828.01百万元降至763.70百万元,占比从9.55%降至7.82%。胸腺肽注射剂、小牛血去蛋白提取物注射液、复合辅酶注射剂、核糖核酸Ⅱ注射剂和人血白蛋白注射液的使用金额3年间均排在前5位,其中胸腺肽注射剂连续3年排名第1。胸腺肽注射剂、小牛血去蛋白提取物注射液的DDDs 3年间均位于前3,但其DDDs已呈下降趋势;而胰激肽原酶注射剂、辅酶Q10注射剂、人血白蛋白注射液、胎盘多肽注射液等的DDDs均呈逐年增长趋势。胸腺肽注射剂的B/A值2013、2015年均为1.00;胰激肽原酶注射剂、辅酶Q10注射剂等的B/A值3年间均远大于1;人血白蛋白注射液、人免疫球蛋白注射液等的B/A值3年间均远小于1,胎盘多肽注射液等的B/A值也均小于1。结论:重庆市34家医院2013-2015年生物制品及生化药品的使用金额总体呈下降趋势,主要品种的临床应用情况基本合理,但对于少数品种的使用仍需加强控制、谨慎选择。
ABSTRACT: OBJECTIVE: To investigate the application and variation trend of biological product and biochemical drugs in hospitals of Chongqing, and to provide reference for further improving rational use of this type of drugs in clinic. METHODS: By using the methods of DDDs analysis and ranking of amount of money, the data on the use of biological products and biochemical drugs collected from 34 hospitals of Chongqing during 2013-2015 were summarized and analyzed statistically. RESULTS: The consumption sum of biological products and biochemical drugs in 34 hospitals from Chongqing during 2013-2015 decreased from 828.01 million yuan to 763.70 million yuan, and their proportion decreased from 9.55% to 7.82%.  The consumption sum of Thymopolypeptides injection, Deproteinised calf blood serum injection, Coenzyme complex injection, Ribonucleic acidⅡinjection and Human albumin injection ranked the top 5 places averagely within 3 years. Among them, Thymopolypeptides injection ranked the top 1 in 3 years. DDDs of Thymopolypeptides injection and Deproteinised calf blood serum injection ranked the top 3 places within 3 years, and DDDs of Thymopolypeptides injection had been declining. DDDs of Kallidinogenase injection, Coenzyme Q10 injection, Human albumin injection and Placental polypeptide injection increased year by year. B/A of Thymosin injection in 2013 and 2015 were both 1.00. B/A of Kallidinogenase injection and Coenzyme Q10 injection were far greater than 1 in 3 years; B/A of Human albumin injection and Human immunoglobulin injection were far less than 1 in 3 years, and those of Placental polypeptide injection were also less than 1. CONCLUSIONS: The consumption sum of biological products and biochemical drugs in 34 hospitals of Chongqing during 2013-2015 are in downward trend generally. The clinical application of the main varieties is basically reasonable, but the application of few varieties needs to be strengthened and chosen carefully.
期刊: 2018年第29卷第12期
作者: 胡蕾,曾钰
AUTHORS: HU Lei,ZENG Yu
关键字: 生物制品;生化药品;利用分析;使用金额;用药频度
KEYWORDS: Biological products; Biochemical drugs; Utilization and analysis; Consumption sum; DDDs
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