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出院后药学干预对基层医院PCI术后冠心病患者用药依从性及其预后的影响
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| 篇名： | 出院后药学干预对基层医院PCI术后冠心病患者用药依从性及其预后的影响 |
| TITLE： | |
| 摘要： | 目的：探讨出院后药学干预对基层医院经皮冠状动脉介入术（PCI）术后冠心病患者用药依从性及其预后的影响。方法：选取2012年1月－2015年5月于我院行PCI的冠心病患者180例，根据其是否接受出院后药学干预分为试验组和对照组，各90例。对照组患者给予常规药学服务和出院教育；试验组患者在此基础上，给予出院后药学干预（包括建立药学服务档案、电话随访、患者教育等），比较出院后1年内两组患者的用药依从性和心血管事件的发生情况。结果：出院后1年内，试验组用药依从的患者比例显著高于对照组，部分依从和不依从的患者比例显著低于对照组；试验组患者1年内心力衰竭和再次血运重建的发生率、住院病死率和全因死亡率均显著低于对照组，差异均有统计学意义（P＜0.05）。结论：出院后药学干预可提高基层医院PCI术后冠心病患者的用药依从性，减少心血管事件的发生，改善其临床预后。 |
| ABSTRACT： | OBJECTIVE： To investigate the effects of pharmaceutical intervention after discharge on medication compliance and prognosis of patients with coronary artery disease after percutaneous coronary intervention（PCI） in primary hospital. METHODS： One hundred and eighty patients with coronary artery disease selected from our hospital after PCI during Jan. 2012 to May 2015 were divided into test group and control group according to whether the patients received pharmaceutical intervention after discharge， with 90 cases in each group. Control group received conventional pharmaceutical care and discharge education. Test group additionally received pharmaceutical intervention（pharmaceutical service files， telephone follow-up， patient education， etc.） after discharge. Medication compliance and occurrence of cardiovascular events were compared between 2 groups in 1 year after discharge. RESULTS： Within 1 year after discharge， the proportion of patients showing good compliance in test group was higher than control group， the proportion of patients showing partial and non compliance in test group were lower than control group； the incidence of heart failure and repeated revascularization， hospitalization mortality and total mortality of test group were significantly lower than control group， with statistical significance （P＜0.05）. CONCLUSIONS： Pharmaceutical intervention after discharge can improve the medication compliance of coronary artery disease patients after PCI in primary hospital， reduce the occurrence of cardiovascular events and improve the clinical prognosis. |
| 期刊： | 2017年第28卷第8期 |
| 作者： | 周树军，王云梅，王振娟，张立强，孔令军，宗文仓，娄志刚 |
| AUTHORS： | ZHOU Shujun，WANG Yunmei，WANG Zhenjuan，ZHANG Liqiang，KONG Lingjun，ZONG Wencang，LOU Zhigang |
| 关键字： | 出院后药学干预；基层医院；冠心病；经皮冠状动脉介入术；用药依从性；预后 |
| KEYWORDS： | Pharmaceutical intervention after discharge； Primary hospital； Coronary artery disease； PCI； Medication compliance； Prognosis |
| 阅读数： | 267 次 |
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