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维生素C片研磨后局部涂抹治疗口腔溃疡的临床观察
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| 篇名： | 维生素C片研磨后局部涂抹治疗口腔溃疡的临床观察 |
| TITLE： | |
| 摘要： | 目的：观察维生素C片研磨后局部涂抹治疗口腔溃疡的临床疗效及安全性。方法：选取2014年2月－2016年2月我院口腔溃疡患者286例，按随机数字表法分为对照组和治疗组，各143例。对照组患者采用桂林西瓜霜局部治疗，每日2～3次；治疗组患者采用维生素C片研磨成粉涂抹患处治疗，每日2～3次。观察两组患者临床疗效、溃疡症状消失时间、不良反应发生率、溃疡复发率和治疗满意度。结果：治疗组患者临床总有效率为96.5％，显著高于对照组的80.4％，差异有统计学意义（P＜0.05）。治疗组患者溃疡症状消失时间为（2.37±0.89） d，显著短于对照组的（4.12±1.33） d；治疗组患者溃疡复发率为3.5％，显著低于对照组的8.4％；治疗组患者治疗满意度为90.9％，显著高于对照组的79.7％，差异均有统计学意义（P＜0.05）。两组患者不良反应发生率比较，差异无统计学意义（P＞0.05）。结论：维生素C片研磨成粉末局部涂抹治疗口腔溃疡疗效显著，能明显缩短溃疡症状消失时间，降低复发率，提高治疗满意度，且安全性较好。 |
| ABSTRACT： | OBJECTIVE： To observe the clinical efficacy and safety of Vitamin C tablets after grinding for local use in the treatment of oral ulcer. METHODS： Two hundved and eighty-six cases of oral ulcer in our hospital during Feb. 2014-Fed. 2016 were selected and divided into treatment group and control group according to random number tabel， with 143 cases in each group. Control group was given Guilin watermellon frost， 2-3 tirnes a day； treatment group was given Vitamin C tablets powder for local use， 2-3 tirnes a day. Clinical efficacy， the time of ulcer disappearance， the incidence of ADR， recurrence rate of ulcer， treatment satisfactory degree were observed in 2 groups. RESULTS： Total response rate of treatment group was 96.5％， which was significantly higher than 80.4％ of control group， with statistical significance （P＜0.05）. The time of ulcer disappearance was （2.37±0.89） d in treatment group， which was significantly shorter than （4.12±1.33） d of control group； recurrence rate of ulcer was 3.5％， which was significantly lower than 8.4％ of control group； treatment satisfactory degree was 90.9％， which was significantly higher than 79.7％ of control group， with statistical significance （P＜0.05）. There was no statistical significance in the incidence of ADR between 2 groups （P＞0.05）. CONCLUSIONS： Vitamin C tablets after grinding for local use has obvious effect on oral ulcer， significantly shortens the time of ulcer disappearance， reduces recurrence rate， and improves treatment satisfactory degree with good safety. |
| 期刊： | 2017年第28卷第8期 |
| 作者： | 黄嘉，李泽贵，彭涛，罗凯颖 |
| AUTHORS： | HUANG Jia，LI Zegui，PENG Tao，LUO Kaiying |
| 关键字： | 维生素C片；口腔溃疡；临床疗效 |
| KEYWORDS： | Vitamin?C?tablet；?Oral?ulcer；?Clinical efficacy |
| 阅读数： | 1025 次 |
| 本月下载数： | 1 次 |
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